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Clinical Article
Research of magnetic resonance perfusion weighted imaging in the characteristics of cervical cancer
YE Yu-feng  CHEN Qiu-mei  XIANG Zhi-ming  LI Jing  HE Cui-wen  GUO Dong-mei  LI Shu-ming 

DOI:10.3969/j.issn.1674-8034.2015.04.011.


[Abstract] Objective: To explore the perfusion differences among cervical cancer, normal cervixand cervical intermural leiomyomas with magnetic resonance.Materials and Methods: We collected 32 cases of cervical cancer patients, 30 cases of normal cervix and 30 cases of patients with cervical intermural leiomyomas.Time signal-intensity curve (TIC), maximum enhancement (ME), steepest slope (SSmax), Time To Peak (TTP), were measured and analyzed on perfusion weighted imaging. Besides, the correlation between characteristics of perfusion and hemodynamic enhancement was calculated.Results: In the TIC type of cervical cancer group, "rapidly wash in followed by a plateau" had 25 cases, "rapidly wash in followed by a slowly wash out" had 7 cases; in the TIC type of normal cervix group, "slow wash in " had 22 cases, "rapidly wash in followed by a plateau" had 8 cases; in the TIC type of cervica intermural leiomyomas group, "rapidly wash infollowed by a plateau" had 24 cases, "slowly wash in " had 6 cases. there are great statistically significant differences between ME, SSmax, TTP of the cervical cancer group and the normal cervix group (P<0.001); there are also great statistically significant differences between cervical cancer group and cervical intermural leiomyomas group (P<0.001).Conclusions: PWI could reflect the hemodynamic characteristics of cervical cancer well, which could help with the differential diagnosis of cervical cancer, and provide the reference for the clinical evaluation.
[Keywords] Perfusion weighted imaging;Magnetic resonance imaging;Cervical cancer;Leiomyomas

YE Yu-feng* Department of Radiology, Panyu District Central Hospital of Guangzhou, Guangzhou 511400, China

CHEN Qiu-mei Department of Ultrasonography, Panyu District Maternal and Child health care Hospital of Guangzhou, Guangzhou 511400, China

XIANG Zhi-ming Department of Radiology, Panyu District Central Hospital of Guangzhou, Guangzhou 511400, China

LI Jing Department of Pathology, Panyu District Central Hospital of Guangzhou, Guangzhou 511400, China

HE Cui-wen Department of Radiology, Panyu District Central Hospital of Guangzhou, Guangzhou 511400, China

GUO Dong-mei Department of Radiology, Panyu District Central Hospital of Guangzhou, Guangzhou 511400, China

LI Shu-ming Department of Radiology, Panyu District Central Hospital of Guangzhou, Guangzhou 511400, China

*Correspondence to: Ye YF, E-mail: 838554325@qq.com

Conflicts of interest   None.

Received  2014-10-25
Accepted  2014-12-26
DOI: 10.3969/j.issn.1674-8034.2015.04.011
DOI:10.3969/j.issn.1674-8034.2015.04.011.

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