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• Review •
Experimental research of superparamagnetic iron oxide for early magnetic resonance imaging diagnosis of hepatocarcinoma
CHEN Zhu  XIAO En-hua 

DOI:10.3969/j.issn.1674-8034.2015.04.014.


[Abstract] Early detection and diagnosis of liver cancer is an important issue that must be addressed. The development of molecular imaging provides a new way for early detection and diagnosis of hepatocellular carcinoma. Superparamagnetic iron oxide(SPIO) has a broad application prospect in biomedical field, and becomes a hot spot in the field of molecular imaging research currently. Compared to traditional magnetic resonance imaging(MRI) contrast medium(gadolinium), SPIO has many advantages, and can lead to negative enhancement for MRI. SPIO has wide applications in the biomedical field and can be used as not only as a drug-release carrier but also as a targeted probe carrier. SPIO has recently gained much attention in the field of molecular imaging research. SPIO is a specific MRI contrast agent for liver imaging and plays an important role in the diagnosis of hepatocellular carcinoma.
[Keywords] Hepatocarcinoma；Superparamagnetic iron oxide；Magnetic resonance imaging；Early diagnosis；Molecular imaging

CHEN Zhu Second Xiangya Hospital of Central South University, Changsha 410011, China

XIAO En-hua* Second Xiangya Hospital of Central South University, Changsha 410011, China

*Correspondence to: Xiao EH, E-mail: cjr.xiaoenhua@vip.163.com

Conflicts of interest   None.

Received  2015-01-14
Accepted  2015-03-02
DOI: 10.3969/j.issn.1674-8034.2015.04.014
DOI:10.3969/j.issn.1674-8034.2015.04.014.

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