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• Clinical Article •
A comparative study of contrast-enhanced and unenhanced MR pulmonary angiography in the diagnosis of pulmonary embolism
YUAN Si-shu  WANG Zi  XIA Li-ming 

DOI:10.3969/j.issn.1674-8034.2015.05.007.


[Abstract] Objective: To evaluate relative detection accuracy of pulmonary embolism (PE) with contrast-enhanced MR angiography (CE-MRA) and unenhanced MR angiography by applying spatial labeling with multiple inversion pulses sequence (SLEEK) imaging.Materials and Methods: Twenty-six patients (15 males and 11 females) with computed tomographic pulmonary angiography (CTPA) diagnosed pulmonary embolism (PE) underwent contrast-enhanced MR pulmonary angiography and SLEEK MR angiography within 48 hours after CTPA. Referring to CTPA, sensitivity, specificity, and positive and negative predictive values for PE detection were calculated and compared for each MR method.Results: Sensitivities for PE detection were 78.8% for contrast-enhanced MR pulmonary angiography and 83.8% for SLEEK MR angiography respectively. Specificities for PE detection were 97.7% for contrast-enhanced MR Pulmonary angiography and 100% for SLEEK MR angiography respectively. Agreement between readers was relatively high (k=0.87).Conclusions: Contrast-enhanced MR pulmonary angiography and SLEEK MR angiography possessed relatively similar sensitivity and specificity. However, considering the non-invasive property of SLEEK MR angiography, where no contrast agent was required, it might become a potential diagnostic strategy for pulmonary embolism.
[Keywords] Magnetic resonance imaging；Pulmonary embolism

YUAN Si-shu Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China

WANG Zi Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China

XIA Li-ming* Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China

*Correspondence to: Xia LM, E-mail: cjr.xialiming@vip.163.com

Conflicts of interest   None.

Received  2015-01-09
Accepted  2015-03-26
DOI: 10.3969/j.issn.1674-8034.2015.05.007
DOI:10.3969/j.issn.1674-8034.2015.05.007.

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