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• Clinical Article •
The study of correlation between ageandanatomical segment in healthy lumbarinterverbraldiscs by diffusion tensor imaging
ZHU Jing-ya  WANG Xiao-ming 

DOI:10.3969/j.issn.1674-8034.2015.07.008.


[Abstract] Objective: Discuss the correlation between lumbar intervertebral disc and age and anatomic site for healthy people with diffusion tensor imaging (DTI).Materials and Methods: Gather 30 healthy adult volunteers with their age range from 21 to 45, which are divided into 5 groups, 21—25, 26—30, 31—35, 36-40 and 41-45. Carry out DTI sequence scanning on them and determine FA and ADC value of each group with MRI software ADW 4.4. Discuss the correlation between above value and age change and different segments of intervertebral disc.Results: With the growth of age, ADC value of L1-S1 declines gradually (Ⅰ : r=-0.470, P<0.01, Ⅱ: r=-0.513, P<0.01, Ⅲ: r=-0.593, P<0.01, Ⅳ: r=-0.697, P<0.01, Ⅴ: r=-0.601, P<0.01), and FA value is not related to age. With the moving down of anatomic segment, at different sites, L1-4 declines slightly and L4—S1 rises obviously, as a whole, it presents a rising trend (F=8.726, P<0.05).Conclusions: ADC value declines with the growth of age. FA value presents a rising trend with the moving down of position and lower intervertebral disc rises obviously. The DTI study indicates that the degenerative change of lumbar intervertebral disc has the correlation with both age and anatomic site.
[Keywords] Lumbar；Intervertebraldisc；Diffusion Tensor Imaging

ZHU Jing-ya Department of Radiology, ShengjingHospital of China Medical University, Shenyang 110004, China

WANG Xiao-ming* Department of Radiology, ShengjingHospital of China Medical University, Shenyang 110004, China

*Correspondence to: Wang XM, E-mail: wangxm024@163.com

Conflicts of interest   None.

Received  2015-04-28
Accepted  2015-06-19
DOI: 10.3969/j.issn.1674-8034.2015.07.008
DOI:10.3969/j.issn.1674-8034.2015.07.008.

[1]
Zhang Z1, Chan Q, Anthony MP, et al. Age-related diffusion patterns in human lumbar intervertebral discs: a pilot study in asymptomatic subjects. Magnetic ResonanceImaging, 2012, 30(18): 181-188.
[2]
Zou J, Yang H, Miyazaki, et al. Dynamic bulging of intervertebral discs in the degenerative lumbar spine. Spine, 2009, 34(23): 2545-2550.
[3]
Brienza M, Pujia F, Colaiacomo MC, et al. 3 T diffusion tensor imaging and electroneurography of peripheral nerve: a morphofunctional analysis in carpal tunnel syndrome. Am J Neuroradiol, 2014, 41(2): 124-130.
[4]
蔡兆熙，陈建宇，蒋新华，等．轴向负荷对腰椎间盘MR扩散特点的影响．中华放射学杂志, 2010, 44(8): 837-840.
[5]
宋春瑶，王晓明．磁共振扩散张量成像对脊髓型颈椎病的初步研究．磁共振成像, 2012, 3(1): 19-23.
[6]
王倩，房俊芳，王滨．磁共振扩散张量成像诊断前列腺癌的理论基础．磁共振成像, 2015, 6(1): 76-80.
[7]
Wu N, Liu H, Chen J, et al.Comparison of apparent diffusion coefficient and T2 relaxation time variation patterns in assessment of age and disc level related intervertebral disc changes. PLoS ONE, 2013, 8(7): e69052.
[8]
李丽，李锋，熊伟．功能MRI在腰椎间盘退变诊断中的应用进展．中国脊柱脊髓杂志, 2010, 20(5): 428-432.
[9]
俎金燕，王晨光，贾宁阳．腰椎间盘退行性变的磁共振弥散张量成像初步研究．中国医学计算机成像杂志, 2013, 19(5): 426-429.
[10]
Eguchi Y, Ohtori S, Orita S, et al. Quantitative evaluation and visualization of lumbar foraminal nerve root entrapment by using diffusion tensor imaging: preliminary results. Am J Neuroradiol, 2011, 32(10): 1824-1829.
[11]
Toshinori S, Ryo M, Eiko Y, et al. DiffusionWeighted Imaging and Diffusion Tensor Imaging of Asymptomatic Lumbar Disc Herniation. J Med Inv, 2014, 61(1-2): 197-203.
[12]
Bosma RL, Stroman PW. Characterization of DTI indices in the cervical, thoracic, and lumbar spinal cord in healthy humans. Radiol Res Pract, 2012(10): 1155-1162.
[13]
John A, Laura M. Michalek J, et al. Analysis of quantitative magnetic resonance imaging and biomechanical parameters on human discs with different grades of degeneration. J Magn Reson Imaging, 2013, 38(6): 1402-1414.
[14]
Kealey SM, Aho T, Delong D, et al. Assessment of apparent diffusion coefficient in normal and degenerated intervertebral lumbar disks: initial experience. Radiology, 2005, 235(2): 569-574.
[15]
蒋新华，陈建宇，蔡兆熙，等．正常人椎间盘MR弥散张量成像ADC值、FA值与年龄和解剖部位的相关性研究．中国CT和MRI杂志, 2009, 7(6): 1-5.
[16]
沈思，王昊，汪飞，等. DWI和DTI对腰椎间盘早期退变的诊断价值.暨南大学学报（医学版）, 2012, 33(4): 409-414.
[17]
Vargas MI, Viallon M, Nguyen D, et al. New approaches in imaging of the brachial plexus. Eur J Radiol, 2010, 74(2): 403-410.
[18]
Niu G, Yu XW, Yang J, et al. Apparent diffusion coefficient in normal and abnormal pattern of intervertebral lumbar discs: initial experience. J Biom Res, 2011, 25(3): 197-203.
[19]
陈丽华，刘爱莲，马春梅，等. DTI评估大鼠肝纤维化及早期肝硬化的实验研究．磁共振成像, 2014, 5(5): 367-371.

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