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• DCE-MRI Quantitative Technique Subject •
Quantitative diagnostic value of 3.0 T dynamic contrast-enhanced MRI in different diagnosis of prostate cancer and hyperplasia
XU Yan  LENG Xiao-ming  ZHENG Yun  ZHAO Man  ZENG Dao-hui  HAN Xiao-rui  FENG Xin  WANG Xiao-chun 

DOI:10.3969/j.issn.1674-8034.2015.08.010.


[Abstract] Objective: To explore the diagnostic value of quantitative analysis parameters of DCE-MRI in prostate cancer diagnosis, and to evaluate the correlation between Ktrans, Kep and Ve and Gleason scores.Materials and Methods: Forty-three prostate diseases patients pathologically proved underwent conventional MRI and DCE-MRI examinations, including 27 patients with prostate cancer and 16 with prostate hyperplasia. The variations of the value of Ktrans, Kep and Ve between the prostate cancer and hyperplastic tissues were measured and compared, and the correlations between Ktrans, Kep and Ve and Gleason scores were studied.Results: The Ktrans, Kep and Ve values of cancerous area were (0.312±0.085) min-1, (0.818±0.098) min-1 and (0.379±0.031), while, for hyperplastic area were (0.213±0.046) min-1, (0.537±0.076) min-1 and (0.324±0.034). The values of Ktrans, Kep, Ve were significantly higher in prostate cancer than in hyperplastic tissues; and Ktrans, Kep, Ve values were not relevant with Gleason score.Conclusion: DCE-MRI quantitative analysis plays a significant role in prostate cancer diagnosis, and may help in differential diagnosis of prostate tumors. Ktrans, Kep and Ve values were not relevant with Gleason score.
[Keywords] Prostate neoplasms；Benign prostatic hyperplasia；Dynamic contrast-enhanced；Magnetic resonance imaging

XU Yan Department of Radiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China

LENG Xiao-ming* Department of Radiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China

ZHENG Yun Department of Radiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China

ZHAO Man Department of Radiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China

ZENG Dao-hui Department of Radiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China

HAN Xiao-rui Department of Radiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China

FENG Xin Department of Radiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China

WANG Xiao-chun Department of Radiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China

*Corresponding author: Leng XM, E-mail: xmleng@hotmail.com

Conflicts of interest   None.

Received  2015-05-30
Accepted  2015-06-28
DOI: 10.3969/j.issn.1674-8034.2015.08.010
DOI:10.3969/j.issn.1674-8034.2015.08.010.

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