Share：
Share this content in WeChat
X
[Chinese][PDF]108682
• Clinical Article •
The preliminary study of role of multi-echo GRE Dixon in the diagnosis of primary hepatocarcinoma
QI Shi  ZHAO Da-wei  ZHAO Jing  YUAN Da  ZHANG Ai-dong  MAO Xiao-xi  SHI Dong-li  LI Hong-jun  LIU Hui 

DOI:10.3969/j.issn.1674-8034.2015.08.014.


[Abstract] Objective: To clarify the significance of multi-echo GRE Dixon in the diagnosis of primary hepatocarcinoma.Materials and Methods: Twenty-two patients with hepatocarcinoma proved pathologically by surgery and biopsy underwent liver MRI scanning with a phase correction multi-echo GRE Dixon sequence. We analyze their imaging features of tumor in water only imaging, fat only imaging, water/fat phase mapping, R2* mapping and make a contrast with imaging of in-phase and opposed-phase, T2 weighted imaging and histopathological results.Results: Intrahepatic cholangiocarcinoma and hepatocellular carcinoma with fatty degeneration usually shows hypointensity on water only imaging and hepatocellular carcinoma without fatty degeneration shows isointensity on water only image. Most of the tumors can be seen more necrosis and hemorrhage on R2* mapping than T2 weighted imaging. The value of R2* of Intrahepatic cholangiocarcinoma is lower than that of Hepatocellular carcinoma and the P value is 0.003. R2* mapping has a lower contrast to noise ratio of tumor and hepatic tissue than T2 weighted imaging.Conclusion: We can distinguish necrosis, hemorrhage, fatty degeneration and fibre in the liver tumor by phase correction multi-echo GRE Dixon, which plays an important role in the differential diagnosis of intrahepatic cholangiocarcinoma and hepatocarcinoma.
[Keywords] Phase correction；GRE Dixon；R2* mapping；Liver neoplasms；Magnetic resonance imaging

QI Shi* Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

ZHAO Da-wei Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

ZHAO Jing Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

YUAN Da Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

ZHANG Ai-dong Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

MAO Xiao-xi Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

SHI Dong-li Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

LI Hong-jun Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

LIU Hui SIEMENS (China) Co., Ltd., Beijing 100102

*Correspondence to: Qi S, E-mail: jarodq@163.com

Conflicts of interest   None.

Received  2015-06-03
Accepted  2015-07-06
DOI: 10.3969/j.issn.1674-8034.2015.08.014
DOI:10.3969/j.issn.1674-8034.2015.08.014.

[1]
张岩岩，张琦，李云芳，等. HBV相关肝硬化结节多步演变MR影像特征研究现状及最新进展．磁共振成像, 2014, 5(3): 232-235.
[2]
蒋涵羽，刘曦娇，宋彬．磁共振成像技术在肝细胞癌中的应用进展.磁共振成像, 2015, 6(2): 91-97.
[3]
Pokharel SS, Macura KJ, Kamel IR, et al. Current MR imaging lipid detection techniques for diagnosis of lesions in the abdomen and pelvis. Radiographics, 2013, 33(3): 681-702.
[4]
McCarville MB, Hillenbrand CM, Loeffler RB, et al. Comparison of whole liver and small region-of-interest measurements of MRI liver R2* in children with iron overload. Pediatr Radiol, 2010, 40(8): 1360-1367.
[5]
Zhong XD, Gilson W, Jellus V, et al. SIEMENS Applications Guide Gre_Dixon_641.2011.
[6]
Dixon TW. Simple proton spectroscopic imaging. Radiology, 1984,153(1):189-194.
[7]
Xiang Q, An L. Water-fat imaging with direct phase encoding. Journal of Magnetic Resonance Imaging, 1997(7):1002-1015.
[8]
Glover GH, Schneider E. Three-point Dixon Technique for true water/fat decoposition with B0 inhomogeneity correction. Magnetic Resonance in Medicine, 1991, 18(2): 371-383.
[9]
Herfkens R, Davis P, Crooks L, et al. Nuclear magnetic resonance imaging of the abnormal live rat and correlations with tissue characteristics. Radiology, 1981, 141(1): 211-218.
[10]
Ohtomo K, Itai Y, Furui S, et al. Hepatic tumors: differentiation by transverse relaxation time (T2) of magnetic resonance imaging. Radiology, 1985, 155(2): 421-423.
[11]
Li RK, Zeng MS, Rao SX, et al. Using a 2D multibreath-hold susceptibility-weighted imaging to visualize intratumoral hemorrhage of hepatocellular carcinoma at 3T MRI: correlation with pathology. J Magn Reson Imaging, 2012, 36(4): 900-906.
[12]
Wells SA. Quantification of hepatic fat and iron with magnetic resonance imaging. Magn Reson Imaging Clin N Am, 2014, 22(3): 397-416.
[13]
Hussain HK, Chenevert TL, Londy FJ, et al. Hepatic fat fraction: MR imaging for quantitative measurement and display--early experience. Radiology, 2005, 237(3): 1048-1055.
[14]
Kirk P, He T, Anderson LJ, et al. International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers. J Magn Reson Imaging, 2010, 32(2): 315-319.
[15]
Jhaveri KS, Cleary SP, Fischer S, et al. Blood oxygen level-dependent liver MRI: can it predict microvascular invasion in HCC?. J Magn Reson Imaging, 2013, 37(3): 692-699.
[16]
Sun M, Wang S, Song Q, et al. Utility of R2* obtained from T2*-weighted imaging in differentiating hepatocellular carcinomas from cavernous hemangiomas of the liver. PLoS One, 2014, 9(3): e91751.

PREV Comparison of HR-MRI, MRA and DSA in measuring intracranial aneurysm
NEXT A study on the best fitting model for diffusion-weighted magnetic resonance imaging of normal prostate tissue at different b-values
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn