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• Clinical Article •
The preliminary study of role of multi-echo GRE Dixon in the diagnosis of primary hepatocarcinoma
QI Shi  ZHAO Da-wei  ZHAO Jing  YUAN Da  ZHANG Ai-dong  MAO Xiao-xi  SHI Dong-li  LI Hong-jun  LIU Hui 

DOI:10.3969/j.issn.1674-8034.2015.08.014.


[Abstract] Objective: To clarify the significance of multi-echo GRE Dixon in the diagnosis of primary hepatocarcinoma.Materials and Methods: Twenty-two patients with hepatocarcinoma proved pathologically by surgery and biopsy underwent liver MRI scanning with a phase correction multi-echo GRE Dixon sequence. We analyze their imaging features of tumor in water only imaging, fat only imaging, water/fat phase mapping, R2* mapping and make a contrast with imaging of in-phase and opposed-phase, T2 weighted imaging and histopathological results.Results: Intrahepatic cholangiocarcinoma and hepatocellular carcinoma with fatty degeneration usually shows hypointensity on water only imaging and hepatocellular carcinoma without fatty degeneration shows isointensity on water only image. Most of the tumors can be seen more necrosis and hemorrhage on R2* mapping than T2 weighted imaging. The value of R2* of Intrahepatic cholangiocarcinoma is lower than that of Hepatocellular carcinoma and the P value is 0.003. R2* mapping has a lower contrast to noise ratio of tumor and hepatic tissue than T2 weighted imaging.Conclusion: We can distinguish necrosis, hemorrhage, fatty degeneration and fibre in the liver tumor by phase correction multi-echo GRE Dixon, which plays an important role in the differential diagnosis of intrahepatic cholangiocarcinoma and hepatocarcinoma.
[Keywords] Phase correction；GRE Dixon；R2* mapping；Liver neoplasms；Magnetic resonance imaging

QI Shi* Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

ZHAO Da-wei Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

ZHAO Jing Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

YUAN Da Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

ZHANG Ai-dong Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

MAO Xiao-xi Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

SHI Dong-li Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

LI Hong-jun Department of Radiology, Beijing YouAn Hospital Affiliated to Capital Medical University, Beijing 100069

LIU Hui SIEMENS (China) Co., Ltd., Beijing 100102

*Correspondence to: Qi S, E-mail: jarodq@163.com

Conflicts of interest   None.

Received  2015-06-03
Accepted  2015-07-06
DOI: 10.3969/j.issn.1674-8034.2015.08.014
DOI:10.3969/j.issn.1674-8034.2015.08.014.

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