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• Clinical Article •
Comparison of susceptibility weighted imaging and TOF-MR angiography for the detection of middle cerebral artery thrombi in acute ischemic stroke
GUO Shu-ning  ZOU Guang-dong  YOU Ke-zeng 

DOI:10.3969/j.issn.1674-8034.2015.09.003.


[Abstract] Objectives: The aim of this study was to compare the diagnostic accuracy of both methods of susceptibility weighted imaging (SWI) and time-of-flight MR angiography (TOF-MRA) in determining middle cerebral artery occlusion in patients with acute ischemic stroke.Materials and Methods: Sixty-one patients who presented with clinical symptoms for acute ischemic stroke in the territory of the middle (M1, M2/M3) cerebral artery (MCA) were performed with conventional MRI, DWI, SWI and TOF-MRA. The frequency of hypointense susceptibility vessel signs (SVS) on SWI and vessel occlusion or stenosis on TOF-MRA were compared using the McNemar test.Results: All of the 61 patients displayed hyperintention on DWI in the infarction area. Forty-seven patients showed larger deep medullary vein than the contralateral. Fifty-nine patients displayed a clearly definable SVS on SWI. In 56 patients the SVS was associated with occlusion or stenosis on TOF-MRA. Sensitivity for detection of thrombi within M1 did not show any significant difference between both techniques (98.2% for both SWI and TOF-MRA) while the sensitivity for detection of thrombi within M2/M3 was significantly different (75.0% for SWI versus 37.5% for TOF-angiography, P<0.05).Conclusions: SWI and TOF-MRA provide similar sensitivity for acute embolic occlusion in stroke while SWI is superior for the detection of embolic occlusion in small, tortuous arterial vessel segments and deep medullary vein.
[Keywords] Brain infarction；Magnetic resonance imaging；Magnetic resonance angiography

GUO Shu-ning Department of Imaging Center, the Yishui Central Hospital, Linyi City, Shandong Province, Linyi 276400, China

ZOU Guang-dong Department of Imaging Center, the Yishui Central Hospital, Linyi City, Shandong Province, Linyi 276400, China

YOU Ke-zeng* Department of Imaging Center, the Yishui Central Hospital, Linyi City, Shandong Province, Linyi 276400, China

*Correspondence to: You KZ, E-mail: youkezenga@163.com

Conflicts of interest   None.

Received  2015-04-21
Accepted  2015-08-06
DOI: 10.3969/j.issn.1674-8034.2015.09.003
DOI:10.3969/j.issn.1674-8034.2015.09.003.

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