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Clinical Article
A study of diffusion tensor imaging characteristics of uterine fibroids with homogeneous hypointense signal on T2WI
LI Jia  LÜ Fu-rong  XIAO Zhi-bo  LÜ Fa-jin  QU Ya-lin  ZHAO Fei-fei 

DOI:10.3969/j.issn.1674-8034.2015.09.008.


[Abstract] Objective: To observe the DTI characteristics of uterine fibroids with homogeneous hypointense signal on T2WI, including the comparison with normal muscle layers, and the difference of DTI parameters between fibroids at different location.Materials and Methods: Sixty-five patients with uterine fibroids were performed routine MRI scanning, enhanced scanning and DTI scan. Eighty uterine leiomyomas were analyzed, including 42 intramural hysteromyoma and 38 subserous fibroids. The fractional anisotropy (FA), mean diffusivity (MD) and relatively anisotropy (RA) of all lesions and normal muscle layers were calculated, all data were analyzed through Independent-Samples t test by SPSS 19.0.Results: MD values of hysteromyomas with homogeneous hypointense signal on T2WI was (1.275±0.204)×10-3 mm2/s, which was significantly lower than the myometrium, FA values (0.465±0.114) and RA values (0.420±0.110) were higher than the myometrium, but there was no significant difference between the parameters of subserous fibroids and intramural hysteromyoma.Conclusions: The DTI characteristics of uterine fibroids with homogeneous hypointense signal on T2WI had some characteristics, which were different with the normal muscle layer, and the location of hysteromyoma did not have much effect on the characteristics of DTI.
[Keywords] Uterine neoplasms;Diffusion magnetic resonance imaging

LI Jia Department of Radiology, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China

LÜ Fu-rong* Department of Radiology, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China

XIAO Zhi-bo Department of Radiology, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China

LÜ Fa-jin Department of Radiology, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China

QU Ya-lin Department of Radiology, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China

ZHAO Fei-fei Department of Radiology, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China

*Correspondence to: Lü FR, E-mail: lfr918@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of the National Clinical Key Subject Construction Project National Health Office of Medical (2013) 544
Received  2015-05-18
Accepted  2015-06-19
DOI: 10.3969/j.issn.1674-8034.2015.09.008
DOI:10.3969/j.issn.1674-8034.2015.09.008.

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