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• Clinical Article •
Correlations between MR apparent diffusion coefficient values and prognostic factors of breast invasive ductal carcinoma
ZHANG Yu  MU Xue-tao  ZHONG Xin  DONG Yu-ru  PENG Pai  WANG Hong 

DOI:10.3969/j.issn.1674-8034.2015.09.010.


[Abstract] Objective: To investigate correlations between apparent diffusion coefficient (ADC) values of invasive ductal carcinoma (IDC) and prognostic factors.Materials and Methods: We examined 47 patients by magnetic resonance imaging (MRI) of breast with pathologically confirmed IDC and measured the ADC values of each lesion. The mean ADC values were cross-check analyzed with the prognostic factors.Results: The mean ADC value was (0.957±0.151)×10-3 mm2/s. The mean ADC values of IDC showed inverse correlation with histological grades (r=0.876, P=0.000) and were significantly lower in the cases with large tumor size (t=2.600, P=0.013), axillary lymph nodes metastasis (t=4.123, P=0.000), ER and PR positive expression (t=3.557, P=0.003. t=3.599, P=0.002). HER-2 expression showed no significant correlation with ADC values (t=1.399, P=0.173).Conclusions: The ADC values were correlated with some prognostic factors and might provide valuable information for the prognosis of IDC.
[Keywords] Carcinoma, ductal, breast；Magnetic resonance imaging

ZHANG Yu Department of MRI, the General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China; Xuzhou Medical College, Xuzhou, Jiangsu 221004, China

MU Xue-tao Department of MRI, the General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China

ZHONG Xin Department of MRI, the General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China

DONG Yu-ru Department of MRI, the General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China

PENG Pai Department of MRI, the General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China; Xuzhou Medical College, Xuzhou, Jiangsu 221004, China

WANG Hong* Department of MRI, the General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China

*Correspondence to: Wang H, E-mail: wanghongmri@sina.com

Conflicts of interest   None.

Received  2015-05-19
Accepted  2015-07-29
DOI: 10.3969/j.issn.1674-8034.2015.09.010
DOI:10.3969/j.issn.1674-8034.2015.09.010.

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