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• Clinical Article •
Application value of DTI tracing the optic tract and optic radiation for the selection of postoperative radiotherapy plan of cerebral gliomas
ZHAO Chao-yun  XIA Xin-she  WANG Ming-lei  LIU Zi-shan  GAO Wen-qi  MA Hui  WANG Xiao-dong  XIA He-chun 

DOI:10.3969/j.issn.1674-8034.2015.10.005.


[Abstract] Objective: To analyze whether the optic tract and the optic radiation showed by diffusion tensor imaging (DTI) can be used to evaluate the value in the guidance of selecting postoperative radiotherapy plan of cerebral gliomas.Materials and Methods: Thirty patients with confirmed cerebral gliomas underwent conventional and contrast-enhanced MRI and DTI before postoperative radiotherapy. In order to delineate the radiotherapy target volume, organs at risk, optic tract and optic radiation, tractography data sets was fused with correlation MR and CT anatomy image by importing it to radiotherapy planning system. The radiotherapy plans developed with intensity modulated radiation therapy (IMRT) and three- dimensional conformal radiotherapy (3D-CRT) techniques were compared.Results: Both the IMRT and the 3D-CRT plans were ensured the therapeutic dose to the target volume and conventional organs at risk had been protected. The doses patients suffered by using the IMRT plan were lower than that of the 3D-CRT plan both in affected,unaffected side optic tract and optic radiation (P<0.05).Conclusion: DTI can display the location, shape of the optic tract and optic radiation, and the relationship with postoperative radiotherapy target volume of cerebral gliomas, and formulate protective treatment plan to reduce the radiation dose suffered by the optic tract and optic radiation, thereby reducing the visual dysfunction risk after radiotherapy.
[Keywords] Cerebral gliomas；Diffusion tensor imaging；Radiotherapy；Optic tract；Optic radiation；Dosimetry

ZHAO Chao-yun Ningxia Medical University, Yinchuan 750004, China

XIA Xin-she Department of Radiation Oncology, General Hospital of Ningxia Medical University, Yinchuan 750004, China

WANG Ming-lei Department of Radiology, General Hospital of Ningxia Medical University, Yinchuan 750004, China

LIU Zi-shan Ningxia Medical University, Yinchuan 750004, China

GAO Wen-qi Ningxia Medical University, Yinchuan 750004, China

MA Hui Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China

WANG Xiao-dong* Department of Radiology, General Hospital of Ningxia Medical University, Yinchuan 750004, China

XIA He-chun Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China

*Correspondence to: Wang XD, E-mail:xdw80@yeah.net

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of the Program of National Natural Science Foundation of China No. 81260373 Natural Science Foundation of Ningxia No. NZ11269
Received  2015-06-01
Accepted  2015-07-30
DOI: 10.3969/j.issn.1674-8034.2015.10.005
DOI:10.3969/j.issn.1674-8034.2015.10.005.

[1]
管西寅，朱国培，冯炎,等.放疗引起眼损伤的研究进展.中华放射肿瘤学杂志, 2010, 19(1): 81-83.
[2]
Bello L, Gambini A, Castellano A, et al. Motor and language DTI fiber tracking combined with intraoperative subcortical mapping for surgical removal of gliomas. Neuroimage, 2008, 39(1): 369-382.
[3]
白雪冬，孙夕林，王丹,等.动态对比增强MRI在鉴别胶质瘤复发及放射性脑损伤中的应用.磁共振成像, 2014, 5(1): 1-6.
[4]
Andrade-Souza YM, Zadeh G, Scora D, et al. Radiosurgery for basal ganglia, internal capsule, and thalamus arteriovenous malformation:Clinical outcome. Neurosurgery, 2005, 56(1): 56-63.
[5]
Jenghwa C, Ashwatha N. Functional MRI for Radiotherapy of Gliomas. Technology in Cancer Research and Treatment, 2010, 9(4): 347-358.
[6]
戴宜武，王振光，秦家振,等.脑胶质瘤治疗进展.中华临床医师杂志(电子版), 2013, 7(14): 6225-6228.
[7]
李文贵，张云亭. fMRI和DTI在脑肿瘤中的联合应用研究.国际医学放射学杂志, 2009, 32(3): 226-228.
[8]
申旭东，沈桂权，高波.脑胶质瘤浸润程度的扩散张量成像研究进展.磁共振成像, 2015, 6(3): 221-224.
[9]
孙胜玉，马辉，王晓东,等. BOLD-fMRI和DTI结合神经导航在枕叶视觉功能区附近病变切除中的应用.中华神经外科杂志, 2011, 27(9): 925-928.
[10]
Lawrence B Marks, Jin Li Ma, et al. Challenges in the clinical application of advanced technologies to reduce radiation-associated normal tissue injury. Int. J. Radiation Oncology Biol. Phys,2007, 69(1):4-12.
[11]
卢洁，吴朝霞，张桂芳,等.脑胶质瘤三维适形放射治疗与调强放射治疗的剂量学比较.中华放射医学与防护杂志, 2009, 29(5): 499-501.
[12]
Shen Q, Ma X, Hu W, et al. Intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy for stage I-II natural killer/T-cell lymphoma nasal type: dosimetric and clinical results. Radiat Oncol, 2013, 25(8): 152.

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