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• Clinical Article •
The value of MR magnetic sensitive technology to identify the cystic renal cell carcinoma and complex renal cysts
TIAN Shi-feng  LIU Ai-lian  LI Ye  LIU Jing-hong  SUN Mei-yu  WANG He-qing  CHEN An-liang  SONG Qing-wei 

DOI:10.3969/j.issn.1674-8034.2015.10.009.


[Abstract] Objective: To explore the value of MR magnetic sensitive technology to identify the cystic renal cell carcinoma (CRCC) and complex renal cysts (CRC).Materials and Methods: Fourteen cases of CRCC and thirteen cases of CRC confirmed by pathology were retrospectively analyzed. The signal performance on T1WI, T2WI, and on magnitude which were generated from enhanced T2 star weighted angiography (ESWAN) data were observed, the Chi-square test was used to compare the difference between each sequence of two groups. The appearance of intratumoral susceptibility signal intensity (ITSS) on the phase map of two groups were observed and scored by two observers, the Kappa test was used to evaluate the consistency of two observers, and the Mann-Whitney U test was used to compare the score difference appearance of ITSS on the phase map of two groups. The values of phase and R2* of two groups were measured by two observers, the data continuity of two groups were measured by the intra-class correlation coefficients (ICC), and used the Mann-Whitney U test to compare various parameters of two groups whether they have statistical difference. Receiver operator characteristic (ROC) curve was used to calculate the cut-off value of phase, R2* and performance of phase, R2* value for distinguishing the CRCC and CRC.Results: The signal performance of CRCC and CRC had no difference on T1WI, T2WI, magnitude map (P>0.05). The consistency of two observers was good (Kappa>0.70), and the score of the appearance of ITSS on the phase map on CRCC (1.93±1.14) was higher than that on CRC (0.77±1.01) (P=0.01). The phase values and R2* values of the two groups obtained from the two observers were in good consistency (ICC>0.70), and the score of the appearance of ITSS on the phase map on CRCC (1.93±1.14) was higher than that on CRC (0.77±1.01) 0.75), the phase and R2* values of CRCC and CRC were -0.030±0.052 and 0.041±0.085, (28.14±8.26) Hz and (15.99±6.29) Hz respectively, the result was statistically significant (P < 0.05). The AUC of phase and R2* values were 0.786, 0.885, the best cut-off values for phase and R2* in characterizing the CRCC from CRC were 0.010 and 17.81 Hz. The sensitivity, specificity were 85.7%, 69.2% and 100.0%, 69.2% respectively.Conclusion: The CRCC and CRC which conventional MR sequences have difficulty to identify, CRCC had more ITSS on phase map. Phase and R2* values can be used as a quantitative index to identify CRCC and CRC, and R2* value is more valuable.
[Keywords] Kidney neoplasms；Kidney, cystic；Magnetic resonance imaging；Susceptibility weighted imaging

TIAN Shi-feng Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

LIU Ai-lian* Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

LI Ye Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

LIU Jing-hong Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

SUN Mei-yu Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

WANG He-qing Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

CHEN An-liang Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

SONG Qing-wei Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

*Correspondence to: Liu AL, E-mail: cjr.liuailian@vip.163.com

Conflicts of interest   None.

Received  2015-08-20
Accepted  2015-09-29
DOI: 10.3969/j.issn.1674-8034.2015.10.009
DOI:10.3969/j.issn.1674-8034.2015.10.009.

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