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• Clinical Article •
The study of multi-b value MR diffusion weighted imaging in differentiation of breast benign and malignant tumors
DAI Hai-yang  LIU Guo-rong  ZHAI Shao-zhi  HUANG Chun-yu  CHEN Shi-sen 

DOI:10.3969/j.issn.1674-8034.2015.11.006.


[Abstract] Objective: To explore the value of multi-b value MR Diffusion Weighted Imaging (DWI) and ADC (apparent diffusion coefficient) in differentiation of breast benign and malignant tumors.Materials and Methods: Thirty-six cases of breast tumors including 24 malignant and 12 benign tumors were collected, all of which were confirmed by biopsy or surgery pathology. All of 4 b values (0, 400, 800, 1000 s/mm2) were performed on DWI examination, and 3 groups of ADC value were generated.Results: The ADC value of malignant tumors was lower than that of benign tumors. There exists statistic significance of ADC value between benign and malignant breast tumors in different b value. The sensitivity and specificity of ADC was 84.7% and 79.8% when b=800 s/mm2 and set 1.33×10-3 mm2/s as the upper bound. And the sensitivity and specificity of ADC was 92.2% and 90.6% when b=1000 s/mm2 and set 1.15×10-3 mm2/s as the upper bound.Conclusions: DWI has great value in the differentiation of breast benign and malignant tumors, and it has most diagnostic accuracy when b was set 1000 s/mm2.
[Keywords] Breast neoplasms；Diffusion magnetic resonance imaging

DAI Hai-yang Department of Medical Imaging, HuiZhou Municipal Central Hospital, Huizhou 516001, China

LIU Guo-rong* Department of Medical Imaging, HuiZhou Municipal Central Hospital, Huizhou 516001, China

ZHAI Shao-zhi Department of Medical Imaging, HuiZhou Municipal Central Hospital, Huizhou 516001, China

HUANG Chun-yu Department of Medical Imaging, HuiZhou Municipal Central Hospital, Huizhou 516001, China

CHEN Shi-sen Department of Medical Imaging, HuiZhou Municipal Central Hospital, Huizhou 516001, China

*Correspondence to: Liu GR, E-mail:liuguorong_888@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This program was supported by science and technology project of Huizhou city No. W2013W27
Received  2015-08-17
DOI: 10.3969/j.issn.1674-8034.2015.11.006
DOI:10.3969/j.issn.1674-8034.2015.11.006.

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