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• Clinical Article •
The MRI features of ischemic lesions of adult moyamoya disease patients in different stage
QIAO Peng-gang  HAN Cong  ZUO Zhi-wei  WANG Yi-tuo  XING Xu-dong  QIAN Tian-yi  LI Gong-jie 

DOI:10.3969/j.issn.1674-8034.2015.12.003.


[Abstract] Objective: To analyze the MRI features of adult moyamoya patients in different stage and possible pathogenesis.Materials and Methods: We retrospectively reviewed the topography of ischemic lesions in 174 cerebral hemispheres of 94 adult patients with moyamoya disease, CVA score were calculated and its correlation with DSA findings were compared.Results: Using the results of DSA as reference, there were 6, 26, 23, 50, 49, 20 cerebral hemispheres in stages I to VI respectively among all 174 cerebral hemispheres. Ischemic lesions were detected in 156 hemispheres: 114 hemispheres only effect sub-cortical structure and 42 hemispheres has cortical areas been involved. There are 145 hemispheres that have lesions located in anterior circulation and 11 hemispheres has lesions in posterior circulation areas. The number of hemispheres whose CVA score is 0-3 are 18, 74, 40, 42 respectively. Along with the increase of stages diagnosed by DSA, the lesions growth from sub-cortical area to cortical area(r=0.32859, P<0.0001), while the CVA score increased as well(r=0.30375, P<0.0001).Conclusion: The location and size of ischemic lesions in patients with moyamoya disease changes along with the progress of DSA grade, which would be helpful to early diagnosis and condition evaluation.
[Keywords] Moyamoya disease；Brain ischemia；Magnetic resonance imaging；Hemodynamics；Cerebrovascular accident；Angiography, Digital subtraction；Adult

QIAO Peng-gang Department of Radiology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China

HAN Cong Department of Neurosurgery, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China

ZUO Zhi-wei Department of Radiology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China

WANG Yi-tuo Department of Radiology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China

XING Xu-dong Department of Radiology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China

QIAN Tian-yi Siemens Healthcare, MR Neuro Applications, Erlangen, Germany, Shenzhen 518057, China

LI Gong-jie* Department of Radiology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China

*Correspondence to: Li GJ, E-mail: ligj307@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of youth project Beijing municipal natural science foundation No. 7144231 Capital characteristic clinic project No. Z141107002514171
Received  2015-09-14
Accepted  2015-10-22
DOI: 10.3969/j.issn.1674-8034.2015.12.003
DOI:10.3969/j.issn.1674-8034.2015.12.003.

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