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• Clinical Article •
Correlative study of clinical-imageological in infantile acute cerebellar ataxia after infection
SUO Ling-yun  LI Li  LI Jing  CHEN Tao  ZHANG Lei  WANG Xiao-hu  REN Hui-peng  REN Zhuan-qin 

DOI:10.3969/j.issn.1674-8034.2015.12.005.


[Abstract] Objective: To investigate the magnetic resonance imaging (MRI) manifestation of infantile acute cerebellar ataxia after infection, and study the correlation of clinic-imageologic.Materials and Methods: The clinical data and imaging manifestation of 30 infant with acute cerebellar ataxia after infection were analyzed retrospectively.Results: The lesion shows hyperintensity signal on T2WI in cerebellar dentate nucleus in all patients. Eighteen cases were cerebellar dentate nucleus lesions, and the long T2 signal was showed in the bridge on the back and sides of the brain-the cerebellum on foot-pulp sail, cerebral peduncle, medulla oblongata, cervical spinaland basal ganglia. Among them, the lesion on the cerebellar dentate nuclei is characteristic, comparing with other parts of the incidence, the difference between groups was significant(P<0.05). If the time span from showing cerebellar symptoms to the preliminary MRI investigation less than 3 days, children had severe clinical symptoms and the lesions wide-ranging, other sites were also involved; The symptoms were improved and the lesions of dentate nucleus range narrow between 3 and 5 days; The children's clinical symptoms improved significantly and the lesions of dentate nucleus disappeared or retracted to the side of the fourth ventricle between 6 and 9 days; The lesions wae disappeared when the time span was more than 9 days, the clinical symptoms of the children were cured or improved significantly. In general, it is positive correlation of clinical-imageological, compared with clinical symptoms, the lesions disappeared faster.Conclusion: There are characteristic imaging manifestations in infantile acute cerebellar ataxia after infection. MRI has an advantage of detecting lesions, also can provide useful information for clinical diagnosis and prognosis.
[Keywords] Child；Cerebellar ataxia；Magnetic resonance imaging

SUO Ling-yun Department of Radiology, Baoji Center Hospital, Baoji 721008, China

LI Li Department of Radiology, Baoji Center Hospital, Baoji 721008, China

LI Jing Department of Radiology, Baoji Center Hospital, Baoji 721008, China

CHEN Tao Department of Radiology, Baoji Center Hospital, Baoji 721008, China

ZHANG Lei Department of Radiology, Baoji Center Hospital, Baoji 721008, China

WANG Xiao-hu Department of Radiology, Baoji Center Hospital, Baoji 721008, China

REN Hui-peng Department of Radiology, Baoji Center Hospital, Baoji 721008, China

REN Zhuan-qin* Department of Radiology, Baoji Center Hospital, Baoji 721008, China

*Correspondence to: Ren ZQ, E-mail: Renzhuanqin@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of science and technology research development plan of Shaanxi province No. 2010k15-06-04
Received  2015-08-20
Accepted  2015-10-18
DOI: 10.3969/j.issn.1674-8034.2015.12.005
DOI:10.3969/j.issn.1674-8034.2015.12.005.

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