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• Clinical Article •
Magnetic resonance imaging and ultrasound in evaluation of microwave ablation therapy for breast benign nodules
ZHANG Wei  LI Jian-min  PAN Xiao-ming  ZHANG Hui  LIANG Ting  LIANG Hai-yun  LU Wei  WANG Da-cheng 

DOI:10.3969/j.issn.1674-8034.2015.12.010.


[Abstract] Objective: To discuss the value of magnetic resonance imaging (MRI) and ultrasound (US) in assessing the efficacy of microwave ablation (MWA) therapy for breast benign nodules.Materials and Methods: Selected 20 patients with 41 benign breast nodules which was confirmed by pathology, before and after MWA therapy, performed US and MRI on those respectively. The following features of the nodule, such as location, number, longest diameter, boundary, internal echoic, etc were observed.Results: The longest diameter of nodules were (17.5±5.6) mm and (15.9±6.9) mm, respectively, they have statistical difference (t=2.752, P=0.012). Before MWA therapy, nodules were all hypoechoic with clearly boundary on gray-scale US, all nodules presented enhancement partly on both contrast-enhanced ultrasound (CEUS) and enhanced MRI imaging. After MWA therapy, therapic region of the nodules were hyperechoic with blur boundary, CEUS presented nodules as non-enhancement in 35 (85%) nodules and sparsely punctate enhancement in 6 nodules, which was undergone further MWA therapy. All nodules were non-enhanced with a area of edema beside the nodules on enhanced MRI. Internal region of the nodule was presented coagulative necrosis on pathology after MWA therapy.Conclusion: MRI can contribute to understand the size, spatial structures and blood flow distribution and US can monitor and assess the process of MWA therapy, they play an important role in designing accurate strategy and evaluating long-term efficacy of MWA therapy.
[Keywords] Breast diseases；Breast nodules；Ultrasonography, mammary；Magnetic resonance imaging；Microwave ablation

ZHANG Wei Department of Interventional Ultrasound, the Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, China

LI Jian-min* Department of Interventional Ultrasound, the Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, China

PAN Xiao-ming Department of Breast and Thyroid Surgery, the Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, China

ZHANG Hui Department of Breast and Thyroid Surgery, the Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, China

LIANG Ting Department of Interventional Ultrasound, the Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, China

LIANG Hai-yun Department of Interventional Ultrasound, the Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, China

LU Wei Department of Pathology, the Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, China

WANG Da-cheng Department of Radiology, the Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, China

*Correspondence to: Li JM, E-mail: 4830380@163.com

Conflicts of interest   None.

Received  2015-09-28
Accepted  2015-11-09
DOI: 10.3969/j.issn.1674-8034.2015.12.010
DOI:10.3969/j.issn.1674-8034.2015.12.010.

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