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• Clinical Article •
Comparison of rectal signet ring cell carcinoma and adenocarcinoma: magnetic resonance imaging features of rectal signet ring cell carcinoma
CAO Wu-teng  WANG Xin-hua  GONG Jia-ying  LI Fang-qian  LI Zhi  MENG Xiao-chun  LIU De-chao  ZHOU Jie  ZHOU Zhi-yang 

DOI:10.12015/issn.1674-8034.2017.08.005.


[Abstract] Objective: To investigate the magnetic resonance (MR) characteristics of primary rectal signet ring cell carcinoma (SRCC), compared with conventional rectal adenocarcinoma (AC).Materials and Methods: 28 cases of rectal SRCC and 31 cases of AC confirmed by pathology with primary rectal MR data were retrospectively analyzed. Compare SRCC with AC about the TNM stage, the basic imaging characteristics and tumor signal from T2WI sequence.Results: In 28 cases of rectal SRCC, the average tumor diameter was 49.33 mm, which exceeded the average 4.03 mm of the rectal intrinsic muscle layer, and the average distance from the lower margin of the tumor to the anal edge was 58.44 mm. The distant metastasis rate of SRCC was 25% (7/28), and the rate of the peritoneal metastasis was 10.7% (3/28). The ratio of the circumferential infiltration more than half of SRCC was higher than AC (92.9% vs 61.3%, P=0.004). The tumor/fat, tumor/muscle and tumor/urine signal ratios of SRCC from T2WI sequence were higher than that of AC respectively. There were no significant differences in the transverse maximum thickness, longitudinal diameter, and the distance of the lower edge of the tumor from anal edge between SRCC and AC. In terms of the distance of tumor breakthrough from the intrinsic muscle layer of the rectum, AC was higher than SRCC (6.03 mm vs 4.03 mm, P=0.044).Conclusion: The rectum circumferential invasion range of SRCC was larger than rectal conventional adenocarcinoma, but the breakthrough of muscular layer distance was relatively limited. The MR T2WI signal of rectal SRCC was often higher than that of conventional adenocarcinoma, which may provide a certain prediction in the differential diagnosis of rectal adenocarcinoma for multidisciplinary therapy.
[Keywords] Rectal neoplasms；Signet ring cell carcinoma；Adenocarcinoma；Magnetic resonance imaging

CAO Wu-teng Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China

WANG Xin-hua Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China

GONG Jia-ying Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China

LI Fang-qian Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China

LI Zhi Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China

MENG Xiao-chun Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China

LIU De-chao Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China

ZHOU Jie Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China

ZHOU Zhi-yang* Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China

*Correspondence to: Zhou ZY, E-mail: zhouzyang@hotmail.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Natural Science Foundation of Guangdong No. 2015A030313109
Received  2017-04-21
Accepted  2017-06-12
DOI: 10.12015/issn.1674-8034.2017.08.005
DOI:10.12015/issn.1674-8034.2017.08.005.

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