Share：
Share this content in WeChat
X
[Chinese][PDF]1146140
• Clinical Article •
Investigating the changes of ALFF of hearing related cortex of infants with sensorineural hearing loss by using fMRI
LIU Mengqiu  LIU Jie  LIU Ying 

Cite this article as: Liu MQ, Liu J, Liu Y. Investigating the changes of ALFF of hearing related cortex of infants with sensorineural hearing loss by using fMRI. Chin J Magn Reson Imaging, 2019, 10(9): 650-654. DOI:10.12015/issn.1674-8034.2019.09.003.


[Abstract] Objective: To study the changes of low frequency amplitude (ALFF) in hearing related brain regions of children with bilateral congenital severe sensorineural deafness (BCSSD) using resting-state functional magnetic resonance imaging (rs-fMRI).Materials and Methods: Twenty-five children (0-4 years old) with BCSSD were recruited in this study and they were divided into two groups: 16 "younger" children with ages below 2 years old and 9 "older" children with ages above 2 years old. Twenty age-matched healthy children (9 in the "younger" group and 11 in the "older" group) were also recruited as controls. All rs-fMRI scans were performed on a 3.0 T GE scanner (discovery 750 w). Data were analyzed to produce ALFF values in different brain regions.Results: In the "younger" group, patients with BCSSD had higher ALFF values compared to healthy controls in left anterior cuneiform lobe, right superior frontal gyrus, right middle occipital gyrus and right parietal lobule. Patients also showed lower ALFF values in left superior temporal gyrus and left inferior frontal gyrus. In the "older" group, patients with BCSSD had higher ALFF values in left anterior cingulate gyrus and left infratemporal gyrus. On the contrary, lower ALFF values were found in left inferior frontal gyrus and left superior temporal gyrus in patients, compared to healthy controls. Comparisons were also performed within the patient group, our results showed that "younger" patients had higher ALFF values in left superior temporal gyrus, left inferior frontal gyrus and insula, and had lower ALFF values in right medial frontal gyrus and left inferior temporal gyrus, compared to "older" patients.Conclusions: The results in this study indicate that functional remodeling may occur in the auditory sensory cortex of children with BCSSD. Functional magnetic resonance imaging can be used as a potential tool to assist preoperative evaluation and prognosis judgement of cochlear implants.
[Keywords] resting state；low frequency amplitude；congenital sensorineural deafness；magnetic resonance imaging

LIU Mengqiu Department of Radiology, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001, China

LIU Jie Department of Radiology, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001, China

LIU Ying* Department of Radiology, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001, China

*Correspondence to: Liu Y, E-mail: felice828@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by the Anhui Province Public Welfare Technology Application Research Linkage Project Fund of 2017 No. 1704f0804003
Received  2019-02-27
Accepted  2019-06-23
DOI: 10.12015/issn.1674-8034.2019.09.003
Cite this article as: Liu MQ, Liu J, Liu Y. Investigating the changes of ALFF of hearing related cortex of infants with sensorineural hearing loss by using fMRI. Chin J Magn Reson Imaging, 2019, 10(9): 650-654. DOI:10.12015/issn.1674-8034.2019.09.003.

[1]
Tan L, Chen Y, Maloney TC, et al. Combined analysis of sMRI and fMRI imaging data provides accurate disease markers for hearing impairment. NeuroImage Clin, 2013, 3: 416-428.
[2]
施剑斌，孙宝春．感音神经性聋患者内耳高分辨率CT检查内耳畸形的分类．听力学及言语疾病杂志, 2017, 25(3): 257-260.
[3]
Fu M, Zuo Y. Experience-dependent structural plasticity in the cortex. Trends Neurosci, 2011, 34(3): 177-187.
[4]
Stephan KE, Hilgetag CC, Burns GA, et al. Computational analysis of functional conectivity between areas of primate cerebral cortex. Philos Trans R Soc Lond B Biol Sci, 2000, 355(1393): 111-126.
[5]
Lonsbury-Martin BL, Martin GK, Coats AC. Chapter 47: The physiology of the auditory and vestibular systems. Ballenger JJ, DOI: . Diseases of the Nose, Throat, Ear, Head and Neck. 13th ed. Philadelphia: Lea and Febiger, 1985: 952-954.
[6]
Holland SK, Plante E, Weber Byars A, et a1. Normal fMRI brain activation pattems in children performing a verb generation task. Neuroimage, 2001, 14(4): 837-843.
[7]
Chilosi AM, Comparini A, Scusa MF, et al. Neurodevelopmental disorders in children with severe to profound sensorineural hearing loss: a clinical study. Dev Med Child Neurol, 2010, 52(9): 856-862.
[8]
Fortnum HM, Marshall DH, Summerfield AQ, et al. Epidemiology of the UK population of hearing-impaired children,including characteristics of those with and without cochlear implants—audiology, aetiology, comorbidity and affluence. Int J Audiol, 2002, 41(3): 170-179.
[9]
Lee DS, Lee JS, Oh SH, et al. Cross-modal plasticity and cochlear implants. Nature, 2001, 409(6817): 149-150.
[10]
Dye MW, Baril DE, Bavelier D. Which aspects of visual attention are changed by deafness? The case of the attentional network test. Neuropsychologia, 2007, 45(8): 1801-1811.
[11]
Hauser PC, Dye MW, Boutla M, et al. Deafness and visual enumeration: not all aspects of attention are modified by deafness. Brain Res, 2007, 1153(1): 178-187.
[12]
Surowiecki VN, Sarant J, Maruff P, et al. Cognitive processing in children using cochlear implants: the relationship between visual memory,attention, and executive functions and developing language skills. Ann Otol Rhinol Laryngol Suppl, 2002, 189: 119-126.
[13]
Bavelier D, Tomann A, Hutton C, et al. Visual attention to the periphery is enhanced in congenitally deaf individuals. J Neurosci, 2000, 20(17): RC93.
[14]
Horn DL, Davis RA, Pisoni DB, et al. Development of visual attention skills in prelingually deaf children who use cochlear implants. Ear Hearing, 2005, 26(4): 389-408.
[15]
Lv SY, Zou QH, Cui JL, et al. Decreased gray matter concentration and local synchronization of spontaneous activity in the motor cortex in Duchenne muscular dystrophy. AJNR Am J Neuroradiol, 2011, 32(11): 2196-2200.
[16]
卢伟，陈丽丽，鲁倩，等．先天性聋人工耳蜗植入儿童皮层听觉诱发电位的研究．中华耳鼻咽喉头颈外科杂志, 2016, 51(4): 241-246.

PREV The value of SWI and 3D-ASL in grading of gliomas
NEXT Preliminary study of magnetic resonance dynamic contrast enhancement combined with diffusion weighted imaging to identify high grade glioma recurrence and treatment-related changes
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn