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• Clinical Article •
The value of SWI and 3D-ASL in grading of gliomas
DU Changyue  MIAO Na  QI Xuhong  DONG Weimin  YU Yang  WEN Zhiyong 

Cite this article as: Du CY, Miao N, Qi XH, et al. The value of SWI and 3D-ASL in grading of gliomas. Chin J Magn Reson Imaging, 2019, 10(9): 645-649. DOI:10.12015/issn.1674-8034.2019.09.002.


[Abstract] Objective: To evaluate the value of susceptibility weighted imaging and three-dimensional arterial spin labeling in identification of gliomas.Materials and Methods: Ninety-two patients with glioma (35 Ⅱ, 13 Ⅲ and 44 Ⅳ) were enrolled. All cases underwent SWI and 3D-ASL scans before operations and were confirmed by postoperative pathology. Intratumoral susceptibility signal intensity (ITSS), the maximal cerebral blood flow value (CBFmax), r1 (CBFmax/unaffected contralateral white matter area CBF1), r2 (CBFmax/unaffected contralateral gray matter area CBF2), r3 (CBFmax/contralateral mirror area normal brain tissue CBF3) were obtained by post-processing. Then did statistical analysis. The value of the ITSS was analyzed by non-parametric Mann-Whitney U test. The values of the 3D-ASL parameters were analyzed by one-way ANOVA. P<0.05 was indicated as the statistically significant difference. Receiver operating characteristic (ROC) curve analysis was used to evaluate the performance of ITSS and 3D-ASL in discriminating between various grades of tumors.Results: The differences of ITSS in (Ⅱ vs. Ⅲ), (Ⅱ vs. Ⅳ) and (Ⅲ vs. Ⅳ) were statistically significant, and higher grades of gliomas showed higher ITSS scores (P<0.05). But the CBFmax, r1, r2 and r3 were statistically significant just in the group of (Ⅱ vs. Ⅳ)(P<0.05). The area under the curve (AUC), sensitivity and specificity of the combination of SWI and 3D-ASL were biggest.Conclusions: By combing SWI and 3D-ASL, the diagnostic efficacy of grading gliomas was greatest than that of a single technique, and SWI was more effective than 3D-ASL.
[Keywords] glioma；neoplasm grading；brain neoplasms；magnetic resonance imaging

DU Changyue Department of Radiology, Capital Medical University Electric Power Teaching Hospital, Beijing 100073, China

MIAO Na Department of Radiology, Capital Medical University Electric Power Teaching Hospital, Beijing 100073, China

QI Xuhong Department of Radiology, Capital Medical University Electric Power Teaching Hospital, Beijing 100073, China

DONG Weimin Department of Radiology, Capital Medical University Electric Power Teaching Hospital, Beijing 100073, China

YU Yang Department of Radiology, Capital Medical University Electric Power Teaching Hospital, Beijing 100073, China

WEN Zhiyong* Department of Radiology, Capital Medical University Electric Power Teaching Hospital, Beijing 100073, China

*Correspondence to: Wen ZY, E-mail: wenzhiyong3329@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article was funded by the Science and Technology Project of State Grid Corporation No. O2017017
Received  2019-01-08
Accepted  2019-06-26
DOI: 10.12015/issn.1674-8034.2019.09.002
Cite this article as: Du CY, Miao N, Qi XH, et al. The value of SWI and 3D-ASL in grading of gliomas. Chin J Magn Reson Imaging, 2019, 10(9): 645-649. DOI:10.12015/issn.1674-8034.2019.09.002.

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