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• Clinical Article •
Application of mTI-ASL technique in differentiating recurrence from radiation injury of brain glioma after operation
BAI Xuefei  GAO Yang  NIU Guangming  WU Qiong  WANG Shaoyu  ZHANG Huapeng 

Cite this article as: Bai XF, Gao Y, Niu GM, et al. Application of mTI-ASL technique in differentiating recurrence from radiation injury of brain glioma after operation. Chin J Magn Reson Imaging, 2020, 11(5): 332-335. DOI:10.12015/issn.1674-8034.2020.05.003.


[Abstract] Objective: In this study, we use multiple inversion time-pulsed arterial spin labeling (mTI-ASL) technique to quantitatively analyze the difference between recurrence and radiation injury of glioma after operation, to further evaluate the value of mTI-ASL technique in differential diagnosis between recurrence and radiation injury of glioma.Materials and Methods: In this study, 20 cases of glioma recurrence, 10 cases of radiation injury subjects were collected. We used Siemens 3.0 T Skyra scanner to collect, mTI-ASL sequence was performed on a 3.0 T MR scanner (Magnetom Skyra, Siemens Healthcare, Erlangen, Germany) after surgery and radiotherapy in patients with glioma. The original image of mTI-ASL was post processed on MATLAB software to obtain CBF and ATT maps. The region of interest was delineated manually by using MRI cron soft ware. Independent sample t-test was used to compare the parameters of the region of interest (ROI) related to recurrence and radiation injury of glioma after operation, and to evaluate the difference of CBF and ATT values of quantitative parameters, so as to evaluate the ability of mTI-ASL technology to differentiate the two parameters.Results: (1) CBF values of recurrence after glioma surgery (6.38±1.41) were higher than those of radiation injury (2.30±0.37). There was significant difference between them (P<0.01). (2) ATT values of recurrence after glioma surgery (0.19±0.30) were higher than the CBF values of radiation injury (0.16±0.12), and the difference was statistically significant (P<0.01).Conclusions: The mTI-ASL technique can distinguish the recurrence and radiation injury of glioma after operation.
[Keywords] magnetic resonance imaging；glioma；postoperative recurrence；brain radiation injury

BAI Xuefei Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010059, China

GAO Yang Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010059, China

NIU Guangming Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010059, China

WU Qiong Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010059, China

WANG Shaoyu Siemens Healthineers, Shanghai 201318, China

ZHANG Huapeng Siemens Healthineers, Shanghai 201318, China

*Correspondence to: Gao Y, E-mail: 1390903990@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  Science Research Project of Inner Mongolia Medical University in 2019 No. NJZY19105 Inner Mongolia Natural Science Foundation Project No. 2018MS08078 Science and Technology Program of Inner Mongolia Autonomous Region No. 2019GG047
Received  2019-09-30
Accepted  2020-03-26
DOI: 10.12015/issn.1674-8034.2020.05.003
Cite this article as: Bai XF, Gao Y, Niu GM, et al. Application of mTI-ASL technique in differentiating recurrence from radiation injury of brain glioma after operation. Chin J Magn Reson Imaging, 2020, 11(5): 332-335. DOI:10.12015/issn.1674-8034.2020.05.003.

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