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3.0 T MRI double-echo hydro-lipid separation Dixon technique for quantitative determination of liver fat in patients with nonalcoholic fatty liver disease
YING Jie  LIU Dan  YANG Quan  WANG Xinglan  DING Zhaojun  SU Liping 

Cite this article as: Ying J, Liu D, Yang Q, et al. 3.0 T MRI double-echo hydro-lipid separation Dixon technique for quantitative determination of liver fat in patients with nonalcoholic fatty liver disease. Chin J Magn Reson Imaging, 2020, 11(7): 577-580. DOI:10.12015/issn.1674-8034.2020.07.020.


[Abstract] Objective: To study the liver fat content in patients with fatty liver by using magnetic resonance water-fat separation Dixon method, and to explore the feasibility and clinical value of the quantitative analysis of the liver fat in the non-alcoholic hepatic steatosis.Materials and Methods: Dixon technique (T1-VIBE-Dixon), a phase (in-phase, IP) and (out-phase, OP) and MRS image were obtained by using conventional liver MRI plain scan and double-echo water-fat separation Dixon technique (T1-VIBE-Dixon). The obtained sequence of Dixon scan obtained the fat fraction map by the software, and the fat score map and the magnetic resonance spectroscopy (MRS) sequence were statistically analyzed for their correlation by the fat fraction (FF) measured at the same position.Results: The correlation coefficient between the FF value measured by the T1-VIBE-Dixon sequence and the FF value measured by 1H-MRS is as high as 0.99637, which is highly correlated.Conclusions: It is feasible to use 3.0 T MRI double-echo water-fat separation Dixon technique in the quantitative analysis of the liver fat in non-alcoholic liver steatosis, and the result is valuable for the diagnosis, follow-up and monitoring of non-alcoholic fatty liver.
[Keywords] Nonalcoholic fatty liver disease；magnetic resonance imaging；Dixon technique；quantitative analysis

YING Jie Department of Radiology, Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing 402160, China

LIU Dan* Department of Radiology, Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing 402160, China

YANG Quan Department of Radiology, Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing 402160, China

WANG Xinglan Department of Radiology, Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing 402160, China

DING Zhaojun Department of Radiology, Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing 402160, China

SU Liping Department of Radiology, Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing 402160, China

*Corresponding to: Liu D, E-mail: 65677676@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by Chongqing Municipal Health and Family Planning Commission Medical Research Project No. 2017MSXMO77
Received  2019-10-29
Accepted  2020-03-25
DOI: 10.12015/issn.1674-8034.2020.07.020
Cite this article as: Ying J, Liu D, Yang Q, et al. 3.0 T MRI double-echo hydro-lipid separation Dixon technique for quantitative determination of liver fat in patients with nonalcoholic fatty liver disease. Chin J Magn Reson Imaging, 2020, 11(7): 577-580. DOI:10.12015/issn.1674-8034.2020.07.020.

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