The effect of different scanning schemes on the image quality in evaluating the relationship between axillary lymph nodes and blood vessels of breast cancer

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• TECHNICAL ARTICLE •

TAN Yuchuan LÜ Fajin YANG Lu DAN Hanli LI Wei

Cite this article as: Tan YC, Lü FJ, Yang L, et al. The effect of different scanning schemes on the image quality in evaluating the relationship between axillary lymph nodes and blood vessels of breast cancer[J]. Chin J Magn Reson Imaging, 2021, 12(2): 62-66. DOI:10.12015/issn.1674-8034.2021.02.014.

Abstract

[Abstract] Objective To evaluate the relationship between axillary lymph nodes and blood vessels in breast cancer by using the technique of mDIXON-MRA, and to explore the influence of different bolus injection rate and delayed scanning time on image quality. Materials andMethods Using Philips INGENIA 3.0 T DNA MR scanner, we collected the MR diffusion weighted imaging (DWI) and vascular imaging of the armpit region of 77 patients with clinically confirmed breast cancer from December 2018 to January 2020. The patients were divided into four groups, and the bolus injection rate was 1.5 mL/s, 2.0 mL/s, 2.5 mL/s, 3.0 mL/s, respectively. After post-processing and reconstruction, two radiologists evaluated and graded the images respectively, measured and calculated signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR), judged the relationship between lymph nodes and peripheral blood vessels, and made statistical analysis based on the gold standard of clinical pathological results.Results The mean values of the four groups (1.5 mL/s, 2.0 mL/s, 2.5 mL/s, 3.0 mL/s) were 1.375±0.405, 1.446±0.375, 1.953±0.351 and 1.422±0.428, respectively. The mean values of SNR were 6.363±0.474, 5.028±0.510, 6.320±0.325, 6.638±0.446, and the mean values of CNR were 4.345±1.670, 5.528±1.794, 5.506±1.143, 5.376±1.569. There was no significant effect on the relationship between axillary lymph nodes and peripheral blood vessels (P＞0.05). Different delayed scanning time showed the difference of axillary vessels (P＜0.05). The average score of early group and late group was 1.561±1.001 and 2.250±1.443, respectively. The average values of SNR were 5.966±1.699, 6.791±1.926, and the average values of CNR were 5.506±0.829, 5.504±0.825. The delay time of early and late group also showed the difference (P＜0.05). Compared with the evaluation results of breast surgery, the best evaluation effect is phase 20, and the evaluation effect is similar from phase 25 to phase 30 and phase 20, and the effect of late delay time is higher than that of early.Conclusions The effect of different injection bolus rate and delayed scanning time on showing the relationship between axillary lymph nodes and blood vessels is different by using mDIXON-MRA technology. In this study, the injection bolus rate of 1.5 mL/s and delayed scanning time of 150 seconds are recommended to be the best.

[Keywords] mDIXON；magnetic resonance angiography；breast cancer；axillary lymph nodes；magnetic resonance imaging

Contributor Information

TAN Yuchuan^{1,
2} LÜ Fajin^1* YANG Lu² DAN Hanli² LI Wei²

¹ Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016 China

² Chongqing Key Laboratory of Tumor Metastasis and Individualized Diagnosis and Treatment Transformation, Cancer Hospital Affiliated to Chongqing University, Chongqing 400030, China

Lü FJ, E-mail: fajinlv@163.com

Conflicts of interest None.

Publication Information

Received 2020-03-24

Accepted 2020-04-24

DOI: 10.12015/issn.1674-8034.2021.02.014

Text

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