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• Clinical Article •
The value of T2 mapping texture features of 3.0 T MRI in grading cartilage injury of knee osteoarthritis
LIU Xiaoyi  PU Rujian  LIANG Jie  JU Wenping  WANG Xianliang 

Cite this article as: Liu XY, Pu RJ, Liang J, et al. The value of T2 mapping texture features of 3.0 T MRI in grading cartilage injury of knee osteoarthritis[J]. Chin J Magn Reson Imaging, 2021, 12(7): 34-38. DOI:10.12015/issn.1674-8034.2021.07.007.


[Abstract] Objective To explore the diagnostic performance of texture analysis based on 3.0 T MRI T2 mapping in different levels of cartilage injury in knee osteoarthritis patients. Materials andMethods Retrospective analysis of experimental group keen osteoarthritis patients (KOA) 72 knee joints and control group healthy volunteers (H) 22 knee joints. Through the sagittal T2 mapping T2 pseudocolor, to draw ROI and mark ICRS grading in a T2 artifact, a total of 201 articular surface images were selected consistent with MRI ICRS grading and arthroscopic grading, OK software was used to extract and analyze texture parameters. According to the ratio of 7∶3, 143 articular surface images were randomly selected as the training set, and the remaining 58 articular surface images were used as the verification set. The parameters of the training set were filtered by Spearman and sbf (select by filter), the characteristics were selected by random forest function, and the model was established by ctree to give the weight of the characteristics in the identification of normal cartilage and different cartilage injury grades. AUC, sensitivity, specificity and accuracy were used to evaluate the performance of the model in predicting normal cartilage and different cartilage injury grades.Results MinLocation, MaxSize and Maximun3DDiameter weights are consistent, among them MinLocation was the largest weight of each damage grade, over 0.75. AUC value of normal cartilage in training set was 0.91, grade Ⅰ damage AUC 0.82, grade Ⅱ damage AUC 0.84, grade Ⅲ damage AUC 0.88; verified that the AUC value of concentrated normal cartilage was 0.87, grade Ⅰ damage AUC 0.74, grade Ⅱ damage AUC 0.84, grade Ⅲ damage AUC 0.96. AUC highest was the validation of the grade Ⅲ damage to cartilage, 0.96. The second was the training of normal cartilage, 0.91. Both in the training set and the verification set show good predictive value. The most sensitive is the injury of cartilage in training set Ⅰ, 0.83 percent. The highest specificity was the injury of cartilage in training set Ⅲ, 0.98.Conclusions Texture parameters extracted by T2 mapping have better ability to distinguish different cartilage damage.
[Keywords] osteoarthritis；texture analysis；magnetic resonance imaging；T2 mapping

LIU Xiaoyi1   PU Rujian2   LIANG Jie1   JU Wenping1   WANG Xianliang1*  

1 Department of Radiology, Weifang People's Hospital, Weifang 261041, China

2 Medical Imaging College ,Weifang Medical College, Weifang 261053, China

Wang XL, E-mail: wangxianliang2011@126.com

Conflicts of interest   None.

Received  2021-02-07
Accepted  2021-03-25
DOI: 10.12015/issn.1674-8034.2021.07.007
Cite this article as: Liu XY, Pu RJ, Liang J, et al. The value of T2 mapping texture features of 3.0 T MRI in grading cartilage injury of knee osteoarthritis[J]. Chin J Magn Reson Imaging, 2021, 12(7): 34-38. DOI:10.12015/issn.1674-8034.2021.07.007.

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