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• Clinical Article •
Study on plaque characteristics of basilar artery with mild and severe curvature based on HR-MRI
ZHANG Dingyue  SUN Jiali  LIU Guoqiang  ZHOU Zhongkai  WANG Wei 

Cite this article as: Zhang DY, Sun JL, Liu GQ, et al. Study on plaque characteristics of basilar artery with mild and severe curvature based on HR-MRI[J]. Chin J Magn Reson Imaging, 2021, 12(11): 12-15, 36. DOI:10.12015/issn.1674-8034.2021.11.003.


[Abstract] Objective To study the differences in the distribution, size and composition of basilar artery (BA) plaques using high resolution magnetic resonance imaging (HR-MRI) among patients with mild and severe BA curvature.Materials and Methods: By three-dimension time of flight magnetic resonance angiography (3D-TOF-MRA), patients with BA curvature were included in the study. The transverse distance from the outer wall of the vessel at the maximum curvature of BA to both ends of BA (the junction line between the top of BA and the confluence of the left and right vertebral arteries) was measured and divided into mild curvature group (5 mm＜transverse distance＜10 mm) and severe curvature group (transverse distance≥10 mm). Clinical factors, plaque distribution (inner arc, outer arc), size (minimal plaque, apparent plaque) and composition [intraplaque hemorrhage (IPH)] were compared between the two groups.Results Ninety-two patients with 106 plaques were enrolled, including 54 patients with 60 BA plaques in the mild BA curvature group and 38 patients with 46 BA plaques in the severe BA curvature group. BA plaques were common in the inner arc between the two groups (inner arc vs. outer arc: 76.7%, 73.9% vs. 23.3%, 26.1%). The plaques were more obvious in the severe BA curvature group than in the mild BA curvature group (severe vs. mild: 65.2% vs. 36.7%), and the difference was statistically significant (P=0.004). The proportion of IPH in the severe BA curvature group was higher than that in the mild BA curvature group (severe vs mild: 69.6% vs. 25.0%), and the difference was statistically significant (P＜0.001). There were no statistically significant differences in clinical related factors between the two groups (P＞0.05).Conclusions The curved basilar atherosclerotic plaques are mostly distributed in the inner arc. Apparent plaques are more likely to occur in the severe BA curvature group than in the mild BA curvature group, and the proportion of IPH in the severe BA curvature group is higher than that in the mild BA curvature group, and the plaque in the mild BA curvature group is more stable.
[Keywords] basilar artery；atherosclerotic；high-resolution；magnetic resonance imaging；plaque

ZHANG Dingyue   SUN Jiali   LIU Guoqiang   ZHOU Zhongkai   WANG Wei*  

Department of Magnetic Resonance, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

Wang W, E-mail: 1391082196@qq.com

Conflicts of interest   None.

Received  2021-05-31
Accepted  2021-09-24
DOI: 10.12015/issn.1674-8034.2021.11.003
Cite this article as: Zhang DY, Sun JL, Liu GQ, et al. Study on plaque characteristics of basilar artery with mild and severe curvature based on HR-MRI[J]. Chin J Magn Reson Imaging, 2021, 12(11): 12-15, 36. DOI:10.12015/issn.1674-8034.2021.11.003.

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