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Advances in imaging differentiation of pseudoprogression and recurrence of brain gliomas after treatment
BAO Shasha  LIU Yifan  LUO Yueyuan  GUO Xiaobin  LI Zhilin  YANG Jun  LIAO Chengde 

Cite this article as: Bao SS, Liu YF, Luo YY, et al. Advances in imaging differentiation of pseudoprogression and recurrence of brain gliomas after treatment[J]. Chin J Magn Reson Imaging, 2021, 12(3): 85-88. DOI:10.12015/issn.1674-8034.2021.03.020.


[Abstract] Glioma, which originates from neuroepithelial cells, is the most common primary tumor in the brain. Its treatment is surgical resection and subsequent simultaneous radiotherapy and chemotherapy, but up to 30% of patients will develop new enhanced lesions in magnetic resonance imaging. This may not be the early tumor progression, but the pseudo progression caused by radiotherapy and chemotherapy Pseudoprogression, due to mild lesions and good prognosis, only needs symptomatic treatment, while tumor recurrence requires re-surgical treatment or other treatment options. If the tumor recurrence and false progression are misdiagnosed, it is likely to delay the best treatment time for patients, and eventually lead to ineffective diagnosis and treatment. Therefore, the correct distinction between recurrence and pseudoprogression of glioma patients is very important for the choice of clinical treatment. It is impossible for conventional magnetic resonance imaging to reliably distinguish PSP from EP. At present, some more advanced imaging methods are expected to identify them accurately.
[Keywords] gliomas；recurrence；pseudoprogression；magnetic resonance imaging；differential diagnosis

BAO Shasha   LIU Yifan   LUO Yueyuan   GUO Xiaobin   LI Zhilin   YANG Jun   LIAO Chengde*  

Yunnan Cancer Hospital (the Third Affiliated Hospital of Kunming Medical University), Kunming 650000, China

Liao CD, E-mail: 846681160@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  Supported by the National Natural Science Foundation of China No.81760316, 82060313 Scientific Research Grant Project of the Key Laboratory of Drug Dependence and Abstinence of the National Health Commission No. 2020DAMARB-005 Yunnan Provincial Health Commissionsupported by the Medical Discipline Leader Project No. D-2018009
Received  2020-11-05
Accepted  2021-01-21
DOI: 10.12015/issn.1674-8034.2021.03.020
Cite this article as: Bao SS, Liu YF, Luo YY, et al. Advances in imaging differentiation of pseudoprogression and recurrence of brain gliomas after treatment[J]. Chin J Magn Reson Imaging, 2021, 12(3): 85-88. DOI:10.12015/issn.1674-8034.2021.03.020.

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