Share：
Share this content in WeChat
X
[Chinese][PDF]72778
• Clinical Article •
Preliminary study of CMR tissue feature tracking technology on left ventricular function in patients with hypertrophic cardiomyopathy with ejection fraction preservation
LIU Yuhao  LI Wei  OUYANG Lina  YANG Qin  WANG Yifan  SUN Xiao  ZHU Li 

Cite this article as: Liu YH, Li W, Ouyang LN, et al. Preliminary study of CMR tissue feature tracking technology on left ventricular function in patients with hypertrophic cardiomyopathy with ejection fraction preservation[J]. Chin J Magn Reson Imaging, 2022, 13(1): 31-36. DOI:10.12015/issn.1674-8034.2022.01.007.


[Abstract] Objective To explore the value of CMR tissue feature tracking technology for left ventricular strain in patients with hypertrophic cardiomyopathy (HCMpEF) with ejection fraction preserved.Materials and Methods: Seventy HCMpEF patients and 42 normal subjects (control group) were scanned with 3.0 T CMR steady-state free precession sequence, and the images were imported into CVI42 post-processing software to measure the basic function parameters of the left heart and the overall 3D strain parameters of the left ventricle. Including: radial, circumferential and longitudinal peak strain (PS), peak systolic strain rate (PSSR), peak diastolic strain rate (PDSR). The SPSS 26.0 software was used for statistical analysis of the two groups of parameters.Results The peak strain in all directions of the HCMpEF group was lower than that of the control group [radial: 26.00 (14.63) vs. 32.39 (10.55), circumferential: (-17.30±4.55) vs. (-19.67±3.73), longitudinal: (-8.14±3.25) vs. (-10.74±3.26), HCMpEF group vs. control group, unit: %], the difference was statistically significant (P＜0.005); the PSSR and PDSR in each direction of HCMpEF group both are lower than the control group [PSSR radial: 1.55 (0.94) vs. 1.85 (0.61), circumferential: -0.99 (0.39) vs. -1.13 (0.29), longitudinal: -0.49 (0.38) vs. -0.67 (0.28), unit: s-1, P＜0.05; PDSR radial: -1.37 (-0.86) vs. -2.17 (1.35), circumferential: 0.87 (2.44) vs. 1.16 (0.53), longitudinal: 0.46 (0.24) vs. 0.68 (0.33), unit: s-1], the difference was statistically significant (P＜0.001).Conclusion Although the ejection fraction is preserved in HCMpEF patients, the systolic and diastolic functions have been impaired. The CMR-FT quantitative analysis technology can provide a new basis for evaluating cardiac function.
[Keywords] cardiovascular magnetic resonance；tissue feature tracking；heart function；strain；hypertrophic cardiomyopathy；ejection fraction

LIU Yuhao1   LI Wei1   OUYANG Lina1   YANG Qin2   WANG Yifan3   SUN Xiao3   ZHU Li3*  

1 Ningxia Medical University, Yinchuan 750000, China

2 Department of Radiology, Gansu Provincial People's Hospital, Lanzhou 730000, China

3 Department of Radiology, General Hospital of Ningxia Medical University,Yinchuan 750000, China

Zhu L, E-mail: zhuli72@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS 2020 Ningxia Natural Science Foundation (No. 2020AAC03420).
Received  2021-06-16
Accepted  2021-11-10
DOI: 10.12015/issn.1674-8034.2022.01.007
Cite this article as: Liu YH, Li W, Ouyang LN, et al. Preliminary study of CMR tissue feature tracking technology on left ventricular function in patients with hypertrophic cardiomyopathy with ejection fraction preservation[J]. Chin J Magn Reson Imaging, 2022, 13(1): 31-36. DOI:10.12015/issn.1674-8034.2022.01.007.

[1]
Maron BJ, Maron MS. Hypertrophic Cardiomyopathy[J]. The Lancet, 2013, 381(9862):242–255. DOI: 10.1016/S0140-6736(12)60397-3.
[2]
Makavos G, Kairis C, Tselegkidi ME, et al. Hypertrophic Cardiomyopathy: An Update Review on Diagnosis,Prognosis,and Treatment[J]. Heart Failure, 2019, 24(4): 439-459. DOI: 10.1007/s10741-019-09775-4.
[3]
Song L, Zou YB, Wang DW, et al. Guidelines for the diagnosis and treatment of adult hypertrophic cardiomyopathy in China[J]. Chin J Cardiol, 2017, 45(12): 1015-1032. DOI: 10.3760/cma.j.issn.0253-3758.2017.12.005.
[4]
The Echocardiography Group of the Chinese Medical Association Ultrasonic Medicine Branch, Echocardiography Professional Committee of Cardiovascular Branch of Chinese Medical Doctor Association. Guidelines for the clinical application of echocardiography in assessing cardiac systolic and diastolic function[J]. Chin J Ultrasonog, 2020, 29(6): 461-477. DOI: 10.3760/cma.j.cn131148-20200227-00115.
[5]
Liu LW. Application status and thinking of echocardiography in clinical management of hypertrophic cardiomyopathy[J]. Chin J Med Ultrasound(Electronic Edition), 2020, 17(5): 385-390. DOI: 10.3877/cma.j.issn.1672-6448.2020.05.001.
[6]
He J, Zhao SH, Lu MJ. Heart MRI Feature Tracking Technology and Its Research Progress[J]. Chin J Magn Reson Imaging, 2020, 11(6): 469-473. DOI: 10.12015/issn.1674-8034.2020.06.018.
[7]
Hinojar R, Fernández-Golfín C, González-Gómez A, et al. Prognostic implications of global myocardial mechanics in hypertrophic cardiomyopathy by cardiovascular magnetic resonance feature tracking. Relations to left ventricular hypertrophy and fibrosis[J]. Int J Cardiol, 2017, 249: 467-472. DOI: 10.1016/j.ijcard.2017.07.087.
[8]
Teng F, Liu T, Dai X. Preliminary study on myocardial strain of hypertrophic cardiomyopathy with characteristic tracing technique of magnetic resonance[J]. Chin J Magn Reson Imaging, 2017, 8(6): 431-435. DOI: 10.12015/issn.1674-8034.2017.06.006.
[9]
Maisch B, Mahrholdt H. ESC-Leitlinie 2014 zur Diagnose und zum Management der hypertrophischen Kardiomyopathie[J]. Herz, 2014, 39(8): 919-930. DOI: 10.1007/s00059-014-4177-z.
[10]
Cerqueira MD, Weissman NJ, Dilsizian V, et al. Standardized Myocardial Segmentation and Nomenclature for Tomographic Imaging of the Heart A Statement for Healthcare Professionals From the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association[J]. Circulation, 2002, 105(4): 539-542. DOI: 10.1161/hc0402.102975.
[11]
Amzulescu MS, De Craene M, Langet H, et al. Myocardial strain imaging: review of general principles, validation, and sources of discrepancies[J]. Eur Heart J Cardiovasc Imaging, 2019, 20(6): 605-619. DOI: 10.1093/ehjci/jez041.
[12]
Faragli A, Tanacli R, Kolp C et al. Cardiovascular magnetic resonance-derived left ventricular mechanics-strain, cardiac power and end-systolic elastance under various inotropic states in swine[J]. J Cardiovasc Magn Reson, 2020, 22(1): 79. DOI: 10.1186/S12968-020-00679-Z.
[13]
Barison A, Aimo A, Todiere G, et al. Cardiovascular magnetic resonance for the diagnosis and management of heart failure with preserved ejection fraction[J]. Heart Fail Rev, 2020-6-22. DOI: . DOI: 10.1007/s10741-020-09998-w.
[14]
Lim C, Blaszczyk E, Riazy L, et al. Quantification of myocardial strain assessed by cardiovascular magnetic resonance feature tracking in healthy subjects-influence of segmentation and analysis software[J]. Eur Radiol, 2021, 31: 3962-3972. DOI: 10.1007/S00330-020-07539-5.
[15]
Cui H, Schaff HV, Lentz CJ, et al. Myocardial Histopathology in Patients With Obstructive Hypertrophic Cardiomyopathy[J]. J Am Coll Cardiol, 2021, 77(17): 2159-2170. DOI: 10.1016/J.JACC.2021.03.008.
[16]
Tops LF, Delgado V ,Marsan NA, et al. Myocardial strain to detect subtle left ventricular systolic dysfunction[J]. Eur J Heart Fail, 2017, 19(3): 307-313. DOI: 10.1002/ejhf.694.
[17]
Cavus E, Muellerleile K, Schellert S, et al. CMR feature tracking strain patterns and their association with circulating cardiac biomarkers in patients with hypertrophic cardiomyopathy[J] .Clin Res Cardiol, 2021: 1-13. DOI: 10.1007/S00392-021-01848-5.
[18]
Smith BM, Dorfman AL, Yu S, et al. Relation of strain by feature tracking and clinical outcome in children, adolescents, and young adults with hypertrophic cardiomyopathy[J]. Am J Cardiol. 2014, 114(8): 1275-1280. DOI: 10.1016/j.amjcard.2014.07.051.
[19]
Sitges M, Ajmone MN, Cameli M, et al. EACVI survey on the evaluation of left ventricular diastolic function[J]. Eur Heart J Cardiovasc Imaging, 2021, 22(10): 1098-1105. DOI: 10.1093/ehjci/jeab087.
[20]
Hu J, Yang SL. The current research status of ultrasound technology in evaluating diastolic function of the heart[J]. J Molecular Imaging, 2020, 43(4): 593-596. DOI: 10.12122/j.issn.1674-4500.2020.04.08.
[21]
Duarte R, Fernandez G. Assessment of left ventricular diastolic function by MR: why,how and when[J]. Insights Imaging, 2010, 1(3): 183-192. DOI: 10.1007/s13244-010-0026-7.
[22]
Playford D, Strange G, Celermajer DS, et al. Diastolic dysfunction and mortality in 436 360 men and women: the National Echo Database Australia (NEDA)[J]. Eur Heart J Cardiovasc Imaging, 2021, 22(5): 505-515. DOI: 10.1093/EHJCI/JEAA253.
[23]
Zhang J, Wang J, Zhu XL, et al. Assessment of left ventricular dysfunction of sarcomere mutation carriers in hypertrophic cardiomyopathy by three-dimensional speckle tracking imaging combined with conventional echocardiography[J]. Chin J Ultrasonogr, 2020, 29(2): 104-109. DOI: 10.3760/cma.j.issn.1004-4477.2020.02.002.

PREV Quantitative assessment of paraspinal muscle fat infiltration in early stage ankylosing spondylitis patients by using MRI IDEAL sequence
NEXT Study on the relationship between signal intensity parameters of liver lobes and albumin-bilirubin grades in magnetic resonance images enhanced with Gd-EOB-DTPA
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn