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Advances in brain functional imaging of abnormal emotional circuits associated with premenstrual dysphoric disorder
CHEN Sirui  XU Xiaowen  ZHAO Yang  XIAO Lei  CHEN Zhenyu  LIAO Hai 

Cite this article as: CHEN S R, XU X W, ZHAO Y, et al. Advances in brain functional imaging of abnormal emotional circuits associated with premenstrual dysphoric disorder[J]. Chin J Magn Reson Imaging, 2024, 15(3): 196-199, 217. DOI:10.12015/issn.1674-8034.2024.03.032.


[Abstract] Premenstrual dysphoric disorder (PMDD) is a unique emotional disease of women, which seriously affects the life and health of women of childbearing age. At present, its pathogenesis is still unclear. Recent studies have shown that the function of affective circuit composed of "prefrontal-anterior cingulate cortex-amygdala-hippocampus-cerebellum" may be closely related to the pathogenesis of PMDD. The paper reviews the brain function of the related brain regions and brain intervals of PMDD, and provide reference for finding the neuropathy mechanism of PMDD.
[Keywords] premenstrual dysphoric disorder；emotional disorder；brain functional imaging；functional magnetic resonance imaging；magnetic resonance imaging；prefrontal cortex；amygdala；neural mechanism

CHEN Sirui   XU Xiaowen   ZHAO Yang   XIAO Lei   CHEN Zhenyu   LIAO Hai*  

Department of Radiology, Guangxi Medical University Cancer Hospital, Nanning 530021, China

Corresponding author: LIAO H, E-mail: 42442427@qq.com

Conflicts of interest   None.

Received  2023-07-03
Accepted  2024-02-23
DOI: 10.12015/issn.1674-8034.2024.03.032
Cite this article as: CHEN S R, XU X W, ZHAO Y, et al. Advances in brain functional imaging of abnormal emotional circuits associated with premenstrual dysphoric disorder[J]. Chin J Magn Reson Imaging, 2024, 15(3): 196-199, 217. DOI:10.12015/issn.1674-8034.2024.03.032.

[1]
LANZA S T, PAERLSTEIN T. Premenstrual dysphoric disorder[J]. Med Clin North Am, 2019, 103(4): 613-628. DOI: 10.1016/j.mcna.2019.02.007.
[2]
KOVACS Z, HEGYI G, SZOKE H. Premenstruális szindróma és premenstruális dysphoriás zavar Premenstrual syndrome and premenstrual dysphoric disorder[J]. Orv Hetil, 2022, 163(26): 1023-1031. DOI: 10.1556/650.2022.32496.
[3]
OSBORN E, BROOKS J, O'BRIEN P M S, et al. Suicidality in women with Premenstrual Dysphoric Disorder: a systematic literature review[J]. Arch Womens Ment Health, 2021, 4(2): 173-184. DOI: 10.1007/s00737-020-01054-8.
[4]
LIPAROTI M, TROISI L E, SARNO L, et al. Functional brain network topology across the menstrual cycle is estradiol dependent and correlates with individual well-being[J]. J Neurosci Res, 2021, 99(9): 2271-2286. DOI: 10.1002/jnr.24898.
[5]
CARLINI S V, DELIGIANNIDIS K M. Evidence-based treatment of premenstrual dysphoric disorder: A concise review[J/OL]. J Clin Psychiatry, 2020, 81(2): 19ac13071 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716347/. DOI: 10.4088/JCP.19ac13071.
[6]
ITRIYEVA K. Premenstrual syndrome and premenstrual dysphoric disorder in adolescents[J/OL]. Curr Probl Pediatr Adolesc Health Care, 2022, 52(5): 101187 [2023-07-03]. https://doi.org/10.1016/j.cppeds.2022.101187. DOI: 10.1016/j.cppeds.2022.101187.
[7]
DAN R, REUVENI I, CANETTI L, et al. Trait-related changes in brain network topology in premenstrual dysphoric disorder[J/OL]. Horm Behav, 2020, 124: 104782 [2023-07-03]. https://doi.org/10.1016/j.yhbeh.2020.104782. DOI: 10.1016/j.yhbeh.2020.104782.
[8]
DUBOL M, EPPERSON C N, LANZENBERGER R, et al. Neuroimaging premenstrual dysphoric disorder: A systematic and critical review[J/OL]. Front Neuroendocrinol, 2020, 57: 100838 [2023-07-03]. https://pubmed.ncbi.nlm.nih.gov/32268180/. DOI: 10.1016/j.yfrne.2020.100838.
[9]
GUO B, ZHANG M, HAO W, et al. Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression[J/OL]. Transl Psychiatry, 2023, 13(1): 5 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829236/. DOI: 10.1038/s41398-022-02297-y.
[10]
FULTON S, DECARIE S L, FIORAMONTI X, et al. The menace of obesity to depression and anxiety prevalence[J]. Trends Endocrinol Metab, 2022, 33(1): 18-35. DOI: 10.1016/j.tem.2021.10.005.
[11]
ARNSTEN A F T, JOYCE M K P, ROBERTS A C. The Aversive Lens: Stress effects on the prefrontal-cingulate cortical pathways that regulate emotion[J/OL]. Neurosci Biobehav Rev, 2023, 145: 105000 [2023-07-03]. https://doi.org/10.1016/j.neubiorev.2022.105000. DOI: 10.1016/j.neubiorev.2022.105000.
[12]
SUZUKI Y, TANAKA S C. Functions of the ventromedial prefrontal cortex in emotion regulation under stress[J/OL]. Sci Rep, 2021, 11(1): 18225 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440524/. DOI: 10.1038/s41598-021-97751-0.
[13]
NEJATI V, MAJIDINEZHAD M, NITSCHE M. The role of the dorsolateral and ventromedial prefrontal cortex in emotion regulation in females with major depressive disorder (MDD): A tDCS study[J]. J Psychiatr Res, 2022, 148: 149-158. DOI: 10.1016/j.jpsychires.2022.01.030.
[14]
KENWOOD M M, KALIN N H, BARBAS H. The prefrontal cortex, pathological anxiety, and anxiety disorders[J]. Neuropsychopharmacology, 2022, 47(1): 260-275. DOI: 10.1038/s41386-021-01109-z.
[15]
PETERSEN N, GHAHREMANI D G, RAPKIN A J, et al. Brain activation during emotion regulation in women with premenstrual dysphoric disorder[J]. Psychol Med, 2018, 48(11): 1795-1802. DOI: 10.1017/S0033291717003270.
[16]
BALLER E B, WEI S M, KOHN P D, et al. Abnormalities of dorsolateral prefrontal function in women with premenstrual dysphoric disorder: a multimodal neuroimaging study[J]. Am J Psychiatry, 2013, 170(3): 305-314. DOI: 10.1176/appi.ajp.2012.12030385.
[17]
GINGNELL M, BANNBERS E, WIKSTROM J, et al. Premenstrual dysphoric disorder and prefrontal reactivity during anticipation of emotional stimuli[J]. Eur Neuropsychopharmacol, 2013, 23(11): 1474-1483. DOI: 10.1016/j.euroneuro.2013.08.002.
[18]
GAO M, QIAO M, AN L, et al. Brain reactivity to emotional stimuli in women with premenstrual dysphoric disorder and related personality characteristics[J]. Aging (Albany NY), 2021, 13(15): 19529-19541. DOI: 10.18632/aging.203363.
[19]
AOKI M, SUZUKI M, SUZUKI S, et al. Cognitive function evaluation in premenstrual syndrome during the follicular and luteal phases using near-infrared spectroscopy[J/OL]. Compr Psychoneuroendocrinol, 2022, 10: 100117 [2023-07-03].https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216448/. DOI: 10.1016/j.cpnec.2022.100117.
[20]
RAPKIN A J, BERMAN S M, MANDELKERN M A, et al. Neuroimaging evidence of cerebellar involvement in premenstrual dysphoric disorder[J]. Biol Psychiatry, 2011, 69(4): 374-380. DOI: 10.1016/j.biopsych.2010.09.029.
[21]
RAPKIN A J, BERMAN S M, LONDON E D. The cerebellum and premenstrual dysphoric disorder[J]. AIMS Neurosci, 2014, 1(2): 120-141. DOI: 10.3934/Neuroscience.2014.2.120.
[22]
ROLLS E T. Emotion, motivation, decision-making, the orbitofrontal cortex, anterior cingulate cortex, and the amygdala[J]. Brain Struct Funct, 2023, 228(5): 1201-1257. DOI: 10.1007/s00429-023-02644-9.
[23]
IBRAHM H M, KULIKOVA A, LY H, et al. Anterior cingulate cortex in individuals with depressive symptoms: A structural MRI study[J/OL]. Psychiatry Res Neuroimaging, 2022, 319: 111420 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724389/. DOI: 10.1016/j.pscychresns.2021.111420.
[24]
ROLLS E T, DECO G, HUANG C C, et al. The human orbitofrontal cortex, vmPFC, and anterior cingulate cortex effective connectome: emotion, memory, and action[J]. Cereb Cortex, 2022, 33(2): 330-356. DOI: 10.1093/cercor/bhac070.
[25]
GINGNELL M, AHLSTEDT V, BANNBERS E, et al. Social stimulation and corticolimbic reactivity in premenstrual dysphoric disorder: a preliminary study[J/OL]. Biol Mood Anxiety Disord, 2014, 4(1): 3 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015856/. DOI: 10.1186/2045-5380-4-3.
[26]
COMASCO E, HAHN A, GANGER S, et al. Emotional fronto-cingulate cortex activation and brain derived neurotrophic factor polymorphism in premenstrual dysphoric disorder[J]. Hum Brain Mapp, 2014, 35(9): 4450-4458. DOI: 10.1002/hbm.22486.
[27]
WEI S M, BALLER E B, MARTINEZ P E, et al. Subgenual cingulate resting regional cerebral blood flow in premenstrual dysphoric disorder: differential regulation by ovarian steroids and preliminary evidence for an association with expression of ESC/E(Z) complex genes[J/OL]. Transl Psychiatry, 2021, 11(1): 206 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032707/. DOI: 10.1038/s41398-021-01328-4.
[28]
SIMIC G, TKALCIC M, VUKIC V, et al. Understanding emotions: Origins and roles of the amygdala[J/OL]. Biomolecules, 2021, 11(6): 823 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228195/. DOI: 10.3390/biom11060823.
[29]
ROLLS E T, DECO G, HUANG C C, et al. Human amygdala compared to orbitofrontal cortex connectivity, and emotion[J/OL]. Prog Neurobiol, 2023, 220: 102385 [2023-07-03]. https://doi.org/10.1016/j.pneurobio.2022.102385. DOI: 10.1016/j.pneurobio.2022.102385.
[30]
HUA J P Y, TRULL T J, MERRILL A M, et al. Functional connectivity between the ventral anterior cingulate and amygdala during implicit emotional conflict regulation and daily-life emotion dysregulation[J/OL]. Neuropsychologia, 2021, 158: 107905 [2023-07-03]. https://doi.org/10.1016/j.neuropsychologia.2021.107905. DOI: 10.1016/j.neuropsychologia.2021.107905.
[31]
ASEDE D, DODDAPANENI D, BOLTON M M. Amygdala intercalated cells: Gate keepers and conveyors of internal state to the circuits of emotion[J]. J Neurosci, 2022, 42(49): 9098-9109. DOI: 10.1523/JNEUROSCI.1176-22.2022.
[32]
YANG L, DUN W, LI K, et al. Altered amygdalar volume and functional connectivity in primary dysmenorrhoea during the menstrual cycle[J]. Eur J Pain, 2019, 23(5): 994-1005. DOI: 10.1002/ejp.1368.
[33]
ZHANG Y, ZHOU W, HUANG J, et al. Neural correlates of perceived emotions in human insula and amygdala for auditory emotion recognition[J/OL]. Neuroimage, 2022, 260: 119502 [2023-07-03]. https://doi.org/10.1016/j.neuroimage.2022.119502. DOI: 10.1016/j.neuroimage.2022.119502.
[34]
WONG J J, WONG N M L, CHANG D H F, et al. Amygdala-pons connectivity is hyperactive and associated with symptom severity in depression[J/OL]. Commun Biol, 2022, 5(1): 574 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187701/. DOI: 10.1038/s42003-022-03463-0.
[35]
YU H, CHEN L, LEI H, et al. Infralimbic medial prefrontal cortex signalling to calbindin 1 positive neurons in posterior basolateral amygdala suppresses anxiety- and depression-like behaviours[J/OL]. Nat Commun, 2022, 13(1): 5462 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482654/. DOI: 10.1038/s41467-022-33139-6.
[36]
PERICO C A, SKAF C R, YAMADA A, et al. Relationship between regional cerebral blood flow and separate symptom clusters of major depression: a single photon emission computed tomography study using statistical parametric mapping[J]. Neurosci Lett, 2005, 384(3): 265-270. DOI: 10.1016/j.neulet.2005.04.088.
[37]
PROTOPOPESCU X, TUECSHER O, PAN H, et al. Toward a functional neuroanatomy of premenstrual dysphoric disorder[J]. J Affect Disord, 2008, 108(1-2): 87-94. DOI: 10.1016/j.jad.2007.09.015.
[38]
GINGNELL M, MORELL A, BANNBERS E, et al. Menstrual cycle effects on amygdala reactivity to emotional stimulation in premenstrual dysphoric disorder[J]. Horm Behav, 2012, 62(4): 400-406. DOI: 10.1016/j.yhbeh.2012.07.005.
[39]
STIERNMN L, DUBOL M, COMASCO E, et al. Emotion-induced brain activation across the menstrual cycle in individuals with premenstrual dysphoric disorder and associations to serum levels of progesterone-derived neurosteroids[J/OL]. Transl Psychiatry, 2023, 13(1): 124 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10101953/. DOI: 10.1038/s41398-023-02424-3.
[40]
ZANELLA F, MONACHESI B, GRECUCCI A. Resting-state BOLD temporal variability in sensorimotor and salience networks underlies trait emotional intelligence and explains differences in emotion regulation strategies[J/OL]. Sci Rep, 2022, 12(1): 15163 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452559/. DOI: 10.1038/s41598-022-19477-x.
[41]
PAN D N, JENTSCH V L, LANGER K, et al. What a difference timing makes: Cortisol effects on neural underpinnings of emotion regulation[J/OL]. Neurobiol Stress, 2023, 25: 100544 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239016/. DOI: 10.1016/j.ynstr.2023.100544.
[42]
DENG D, PANG Y, DUAN G, et al. Larger volume and different functional connectivity of the amygdala in women with premenstrual syndrome[J]. Eur Radiol, 2018, 28(5): 1900-1908. DOI: 10.1007/s00330-017-5206-0.
[43]
PETERSEN N, GHAHREMANI D G, RAPKIN A J, et al. Resting-state functional connectivity in women with PMDD[J/OL]. Transl Psychiatry, 2019, 9(1): 339 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906514/. DOI: 10.1038/s41398-019-0670-8.
[44]
MATEUS-PINHEIRO A, PATRICIO P, ALVES N D, et al. Hippocampal cytogenesis abrogation impairs inter-regional communication between the hippocampus and prefrontal cortex and promotes the time-dependent manifestation of emotional and cognitive deficits[J]. Mol Psychiatry, 2021, 26(12): 7154-7166. DOI: 10.1038/s41380-021-01287-8.
[45]
GOTHARD K M, FUGLEVAND A J. The role of the amygdala in processing social and affective touch[J]. Curr Opin Behav Sci, 2022, 43: 46-53. DOI: 10.1016/j.cobeha.2021.08.004.
[46]
LI Y D, LUO Y J, CHEN Z K, et al. Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior[J]. Nat Neurosci, 2022, 25(5): 630-645. DOI: 10.1038/s41593-022-01065-x.
[47]
LONG J, WANG Y, LIU L, et al. The prominent role of the temporal lobe in premenstrual syndrome and premenstrual dysphoric disorder: Evidence from multimodal neuroimaging[J/OL]. Front Psychiatry, 2022, 13: 954211 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274249/. DOI: 10.3389/fpsyt.2022.954211.
[48]
JEONG H G, HAM B J, YEO H B, et al. Gray matter abnormalities in patients with premenstrual dysphoric disorder: an optimized voxel-based morphometry[J]. J Affect Disord, 2012, 140(3): 260-267. DOI: 10.1016/j.jad.2012.02.010.
[49]
WEI S, SUN P, GUO Y, et al. Gene expression in the hippocampus in a rat model of premenstrual dysphoric disorder after treatment with baixiangdan capsules[J/OL]. Front Psychol, 2018, 9: 2065 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242977/. DOI: 10.3389/fpsyg.2018.02065.
[50]
SYAN S K, MINUZZI L, SMITH M, et al. Brain structure and function in women with comorbid bipolar and premenstrual dysphoric disorder[J/OL]. Front Psychiatry, 2018, 8: 301 [2023-07-03]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768056/. DOI: 10.3389/fpsyt.2017.00301.

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