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• Clinical Article •
Evaluation of left ventricular strain and its diagnostic value in dilated cardiomyopathy by cardiovascular magnetic resonance feature tracking technology
ZHONG Ying  WANG Guan  DAI Xu 

Cite this article as: Zhong Y, Wang G, Dai X. Evaluation of left ventricular strain and its diagnostic value in dilated cardiomyopathy by cardiovascular magnetic resonance feature tracking technology[J]. Chin J Magn Reson Imaging, 2021, 12（7）: 6-11. DOI:10.12015/issn.1674-8034.2021.07.002.


[Abstract] Objective To evaluate left cardiac function, left ventricular 3D strain and the diagnostic value of strain for non-ischemic dilated cardiomyopathy (NIDCM) in patients with NIDCM based on cardiovascular magnetic resonance feature tracking technology (CMR-FT). Materials andMethods Thirty-three patients (NIDCM group) and 33 healthy volunteers (control group) were enrolled in this study underwent CMR to compare the left ventricular function and strain parameters of the two groups. According to LGE results, the left ventricular myocardium in the NIDCM group was divided into LGE positive (164) and LGE negative (364) groups according to the 17-segment segmentation method, and the 3D strain parameters of the two groups were compared. Repeatability test, inter-group and intra-group mean comparison, Pearson correlation analysis, Logistic regression model and receiver operating characteristic (ROC) curve analysis were performed for each group.Results The 3D global strain in NIDCM group were lower than those in control group, the differences between the two groups were significant (P＜0.001). Left ventricular ejection fraction (LVEF) in NIDCM group was significantly lower than that in control group (P＜0.001), left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV) and left ventricular mass (LVM) in the control group were higher than those in the control group (all P＜0.001). The LVEF in NIDCM group was negatively correlated with the GCS (P＜0.01). There were significant differences in RS, CS and LS between LGE positive and LGE negative segments in NIDCM group (all P＜0.05). RS of LGE positive myocardial segments had certain diagnostic value in the diagnosis of NIDCM positive myocardial segments (AUC=0.785), there was no significant diagnostic value for CS and LS (AUC=0.584, 0.665, respectively). The combined diagnosis of RS and CS had certain diagnostic value (AUC=0.789), RS and LS (AUC=0.811), CS and LS (AUC=0.712). The combined diagnostic value of RS, CS and LS (AUC=0.810) was nearly consistent with that of RS and LS.Conclusions Strain analysis using CMR-FT has good repeatability. LVEF in NIDCM group was strongly correlated with left ventricular GCS. Strain analysis using CMR-FT technology can identify myocardial fibrosis in patients with NIDCM without contrast agent and has potential clinical value.
[Keywords] dilated cardiomyopathy；cardiovascular magnetic resonance feature tracking technology；cardiovascular magnetic resonance imaging；strain

ZHONG Ying   WANG Guan   DAI Xu*  

Department of Radiology, the First Affliated Hospital of China Medical University, Shenyang 110001, China

Dai X, E-mail: daixudex@vip.sina.com

Conflicts of interest   None.

Received  2021-01-07
Accepted  2021-03-18
DOI: 10.12015/issn.1674-8034.2021.07.002
Cite this article as: Zhong Y, Wang G, Dai X. Evaluation of left ventricular strain and its diagnostic value in dilated cardiomyopathy by cardiovascular magnetic resonance feature tracking technology[J]. Chin J Magn Reson Imaging, 2021, 12（7）: 6-11. DOI:10.12015/issn.1674-8034.2021.07.002.

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